DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12229 and AT3G04050

DIOPT Version :9

Sequence 1:	NP_648980.1	Gene:	CG12229 / 39945	FlyBaseID:	FBgn0036723	Length:	571	Species:	Drosophila melanogaster
Sequence 2:	NP_187055.1	Gene:	AT3G04050 / 819560	AraportID:	AT3G04050	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	524	Identity:	115/524 - (21%)
Similarity:	200/524 - (38%)	Gaps:	146/524 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 NGTYTFHVDTVGNKPDELKAILDTMNIAISAHSAERELRLTTGLALEINGECCRVGRLRNNCTVM 160
            :|::::|.:|:    |.|:..::...|..:             :.|:..|...|.|.|:....|.
plant    51 HGSHSYHQETL----DNLRTAMENTCIPCA-------------VMLDTKGPEIRTGFLKEGKPVE 98

  Fly   161 LARGGVVTLTTDESYRYKGFKEIVYVINLRCYLASVQLGDIVMIGREVRGKVVKTLREALTVMII 225
            |.:|..:|::||  |..:|....: .::.:.....::.||:::..   .|.:      :|||:..
plant    99 LIQGQEITISTD--YTMEGDSNTI-SMSYKKLAEDLKSGDVILCS---DGTI------SLTVLSC 151

  Fly   226 DAGL------------VASYDFIELPRQCHALDPDLYPDLYMKD----LEMAASLNANYVVLPKI 274
            |..|            :.....:.||    .:..|| |.|..||    |:.......:.:.|..:
plant   152 DKNLGLVRARCENSAVLGERKNVNLP----GIVVDL-PTLTEKDQEDILQWGVPNKIDIIALSFV 211

  Fly   275 RCKSFLRAVRQTLNSDF-NLKLIGMIDFEYVRSNMLDLLGIIKLVDYIWIPDMFNVNCCVYNYIM 338
            |..|.|..||:.|..:. ::.|:..::      |...::...|:::|   .|.|.|       ..
plant   212 RKGSDLVEVRKLLGENAKSIMLMSKVE------NQEGVMNFDKILEY---SDAFMV-------AR 260

  Fly   339 EDV---LPISQ---CQK----------KPVI-GTVPLERCSDF---KRFELHD----FLWKVDAI 379
            .|:   :||.:   .||          ||:: .|..||..:..   .|.|..|    .|...|.:
plant   261 GDLGMEIPIEKMFLAQKMMIQKANALGKPIVTATQMLESMTKSPRPTRAEATDVANAVLDGTDCV 325

  Fly   380 HIQKSPWCNKYP--------LIVKKLMPIKDYRVGAVQNKMVLKSILTSYQTIVNFIIRTISSIE 436
            .:........:|        .|.|:.....||.              |.::.|.:.:...:|.||
plant   326 MLSGETAAGAHPETAVLTMSRICKEAEDFIDYD--------------TMHKKIQDIVSLPLSPIE 376

  Fly   437 CQAIFLFTT----CETASVALSR----IEI---YCP----VYVMVP-LEETDDAETITCK---VE 482
            ..|....:|    |..|.|.|::    :|:   |.|    :.|:|| :..|||.|. :|.   ..
plant   377 SLAASAVSTARSLCAAAIVVLTKGGYTVELVAKYRPSVPILSVIVPEITRTDDFEW-SCSESAAH 440

  Fly   483 LARALHLRRNMHPVLYT--------KDLNECSYSPIEFGVDFMRKKGCLEVGDFVVTLEVGKEDK 539
            :||...:.|.:.||:.|        ||..|   ..|:|.::|.:|||..:.||.:|.|.  |.|.
plant   441 VARRGLIYRGIVPVMATGASARSSNKDSTE---ETIQFAIEFAKKKGICKTGDSIVALH--KIDG 500

  Fly   540 DNVV 543
            .:||
plant   501 SSVV 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12229	NP_648980.1	pyruv_kin	103..530	CDD:273424	107/502 (21%)
CG12229	NP_648980.1	Pyruvate_Kinase	126..530	CDD:304951	103/479 (22%)
AT3G04050	NP_187055.1	PLN02461	1..510	CDD:215255	115/524 (22%)
AT3G04050	NP_187055.1	Pyruvate_Kinase	17..496	CDD:304951	110/512 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0469
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11817
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870