Protein Alignment CG12229 and pkmb

DIOPT Version :9

• Sequence 1: NP_648980.1
• Gene: CG12229 / 39945
• FlyBaseID: FBgn0036723
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: XP_005163170.3
• Gene: pkmb / 445094
• ZFINID: ZDB-GENE-040801-230
• Length: 605
• Species: Danio rerio
• Alignment Length: 538
• Identity: 111/538 - (20%)
• Similarity: 194/538 - (36%)
• Gaps: 160/538 - (29%)

  Fly    88 DELRRML-----------ENGTYTFHVDTVGNKPDELKAI----LDTMNIAISAHSAERELRLTT 137
            :.||.|:           .:||:.:|.:|:.:..:.:::.    :|...:||
Zfish   133 ETLREMILSGMNVARLNFSHGTHEYHAETIKSVREAIESFGAGTIDYRPVAI------------- 184

  Fly   138 GLALEINGECCRVGRLRNNCT--VMLARGGVVTLTTDESYR--------YKGFKEIVYVINLRCY 192
              ||:..|...|.|.::.:.|  |.|.:|.::.||.|:.:.        :..:|.|..|
Zfish   185 --ALDTKGPEIRTGLIKGSGTEEVKLVKGNIIKLTLDDKFMDNCDENTLWLDYKNITKV------ 241

  Fly   193 LASVQLGDIVMIGREVRGKVVKTL-REALTVMIIDAGLVASYDFIELPRQCHALDPDLYPDLYMK 256
               ||.|..:.:...:....||.: .:.|...|.:.|::.|...:.||..  .:|.....:..:|
Zfish   242 ---VQQGSHIYVDDGLISLKVKEIGSDFLNCEIENGGMLGSKKGVNLPGA--NVDLPAVSEKDIK 301

  Fly   257 DLEMAASLNANYVVLPKIRCKSFLRAVRQTL-NSDFNLKLIGMID-FEYVRSNMLDLLGIIKLVD 319
            ||:.......:.|....||..:.:.|||:.| ....::::|..:: .|.||.  .|  .|::..|
Zfish   302 DLQFGVEQGVDMVFASFIRKAADVHAVRKVLGEKGKDIRIISKLENHEGVRK--FD--EILEASD 362

  Fly   320 YIWIP--DMFNVNCCVYNYIMEDVLPISQCQK--KPVI-GTVPLERCSDFK-----RFELHD--- 371
            .|.:.  |: .:........:...:.||:|.:  ||:| .|..||  |..|     |.|..|
Zfish   363 GIMVARGDL-GIEIPTEKVFLAQKMMISRCNRIGKPIICATQMLE--SMIKKPRPTRAESSDVAN 424

  Fly   372 -FLWKVDAIHIQKSPWCNKYPL---IVKKLM--------------------------PIKDYRVG 406
             .|...|.|.:.......:||:   :.:.|:                          |.:...||
Zfish   425 AVLDGADCIMLSGETAKGEYPIESVLTQHLIAREAEAAMFHRQLFEELRRTSHLTRDPTESVAVG 489

  Fly   407 AVQNKMVLKSILTSYQTIVNFIIRTISSIEC--QAIFLFTTCETASVALSRIEIYCPVYVMVPLE 469
            ||:                       :|.:|  .||...|....::..|||.....|:.
Zfish   490 AVE-----------------------ASFKCCASAIICLTKTGRSAQLLSRYRPRAPIM------ 525

  Fly   470 ETDDAETITCKVELARALHLRRNMHPVLYTKDLNECSYSPIEFGVDFMRKKGCLEVGDFVVTLEV 534
                  .:|...:.:|.|||.|.:.|:||||..|:.....::..|.|              .||:
Zfish   526 ------AVTRNGQTSRQLHLYRGVIPILYTKPANDIWAEDVDLRVSF--------------ALEI 570

  Fly   535 GKEDK-----DNVVIGIG 547
            ||..|     |.:::..|
Zfish   571 GKHRKYFKSGDVIIVVTG 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12229	NP_648980.1	pyruv_kin	103..530	CDD:273424	98/488 (20%)
		Pyruvate_Kinase	126..530	CDD:304951	94/461 (20%)
pkmb	XP_005163170.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11817
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010