Protein Alignment CG12229 and PyK

DIOPT Version :9

• Sequence 1: NP_648980.1
• Gene: CG12229 / 39945
• FlyBaseID: FBgn0036723
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: NP_524448.3
• Gene: PyK / 42620
• FlyBaseID: FBgn0267385
• Length: 533
• Species: Drosophila melanogaster
• Alignment Length: 493
• Identity: 118/493 - (23%)
• Similarity: 202/493 - (40%)
• Gaps: 95/493 - (19%)

  Fly    91 RRMLENGTYTFHVDTVGNKPDELKAILDTMNIAISAHSAERELRLTTGLALEINGECCRVGRLRN 155
            |....:|::.:|..||.|           :..|:..:||:........:||:..|...|.|.:..
  Fly    76 RMNFSHGSHEYHAATVAN-----------VRQAVKNYSAKLGYEHPVAIALDTKGPEIRTGLIGG 129

  Fly   156 NCT--VMLARGGVVTLTTDESYRYKGFKEIVYV-----INL-----RCYLASVQLGDIVMIGREV 208
            :.|  :.|.:|..:.|||::.:..||..|||||     :|:     |.:   |..|.|.:|.|||
  Fly   130 SGTAEIELKKGEKIKLTTNKEFLEKGSLEIVYVDYENIVNVVKPGNRVF---VDDGLISLIVREV 191

  Fly   209 RGKVVKTLREALTVMIIDAGLVASYDFIELPRQCHALDPDLYPDLYMK---DLEMAASLNANYVV 270
             ||      ::||..:.:.|.:.|...:.||    .:..|| |.:..|   ||........:.:.
  Fly   192 -GK------DSLTCEVENGGSLGSRKGVNLP----GVPVDL-PAVSEKDKSDLLFGVEQEVDMIF 244

  Fly   271 LPKIRCKSFLRAVRQTL-NSDFNLKLIGMIDFEYVRSNMLDLLGIIKLVDYIWIP--DMFNVNCC 332
            ...||..:.|..:|:.| ....|:|:|..|:.:   ..|.:|..||:..|.|.:.  |: .:...
  Fly   245 ASFIRNAAALTEIRKVLGEKGKNIKIISKIENQ---QGMHNLDEIIEAGDGIMVARGDL-GIEIP 305

  Fly   333 VYNYIMEDVLPISQCQK--KPVI-GTVPLERCSDFK-----RFELHD----FLWKVDAIHIQKSP 385
            .....:.....|::|.|  |||| .|..||  |..|     |.|:.|    .|...|.:.:....
  Fly   306 AEKVFLAQKAMIARCNKAGKPVICATQMLE--SMVKKPRPTRAEISDVANAVLDGADCVMLSGET 368

  Fly   386 WCNKYPL--IVKKLMPIKDYRVGAVQNKMVLKSILTSYQTIVNFIIRTISSIE------CQAIFL 442
            ...:|||  ::......|:.. .|:.::.:...::....||.......|:::|      ..||.:
  Fly   369 AKGEYPLECVLTMAKTCKEAE-AALWHQNLFNDLVRGAGTIDASHAAAIAAVEAATKAKASAIVV 432

  Fly   443 FTTCETASVALSRIEIYCPVYVMVPLEETDDAETITCKVELARALHLRRNMHPVLY--------T 499
            .||...::..:|:....||:..:....:|            ||..||.|.:.|::|        .
  Fly   433 ITTSGKSAFQVSKYRPRCPIIAVTRFAQT------------ARQAHLYRGLVPLIYKEPGLGDWL 485

  Fly   500 KDLNECSYSPIEFGVDFMRKKGCLEVGDFVVTLEVGKE 537
            ||::    ..::||:...:|.|.::.||.||.:...|:
  Fly   486 KDVD----VRVQFGLQVGKKNGFIKTGDSVVVVTGWKQ 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12229	NP_648980.1	pyruv_kin	103..530	CDD:273424	112/472 (24%)
		Pyruvate_Kinase	126..530	CDD:304951	108/449 (24%)
PyK	NP_524448.3	Pyruvate_Kinase	46..532	CDD:238178	118/493 (24%)
		pyruv_kin	46..529	CDD:273424	118/493 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0469
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11817
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910