Protein Alignment CG12229 and pkma

DIOPT Version :9

• Sequence 1: NP_648980.1
• Gene: CG12229 / 39945
• FlyBaseID: FBgn0036723
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: NP_955365.1
• Gene: pkma / 335817
• ZFINID: ZDB-GENE-031201-4
• Length: 532
• Species: Danio rerio
• Alignment Length: 501
• Identity: 111/501 - (22%)
• Similarity: 193/501 - (38%)
• Gaps: 103/501 - (20%)

  Fly    88 DELRRMLE-----------NGTYTFHVDTVGNKPDELKAILDTMNIAISAHSAERELRLTTGLAL 141
            |.|:.|::           :|::.:|.:|:.|          ......|......:.| ..|:||
Zfish    60 DTLKEMIKSGMNIARMNFSHGSHEYHGETIKN----------VREACASFEPGSIQYR-PVGIAL 113

  Fly   142 EINGECCRVGRLRNNCT--VMLARGGVVTLTTDESYR-----------YKGFKEIVYVINLRCY- 192
            :..|...|.|.::.:.|  |.|.:|..:.:|.|:|:.           ||...::|.| ..:.|
Zfish   114 DTKGPEIRTGLIKGSGTAEVELKKGNKIKVTLDDSFMENCDEDTLWLDYKNITKVVEV-GSKVYI 177

  Fly   193 ---LASVQLGDIVMIGREVRGKVVKTLREALTVMIIDAGLVASYDFIELPRQCHALDPDLYPDLY 254
               |.|:|   ::.||.:.           |...|.:.|.:.|...:.||..  |:|.....:..
Zfish   178 DDGLISLQ---VLQIGSDY-----------LICEIENGGSLGSKKGVNLPGA--AVDLPAVSEKD 226

  Fly   255 MKDLEMAASLNANYVVLPKIRCKSFLRAVRQTL-NSDFNLKLIGMID-FEYVRSNMLDLLGIIKL 317
            :|||:....:..:.:....||..:.::|||:.| ....|:|:|..:: .|.||  ..|  .|::.
Zfish   227 IKDLQFGVEMGVDMIFASFIRKAADVQAVRKVLGEKGKNIKIISKLENHEGVR--RFD--EIMEA 287

  Fly   318 VDYIWIP--DMFNVNCCVYNYIMEDVLPISQCQK--KPVI-GTVPLERCSDFK-----RFELHD- 371
            .|.|.:.  |: .:........:...:.|.:|.|  ||:| .|..||  |..|     |.|..|
Zfish   288 SDGIMVARGDL-GIEIPTEKVFLAQKMMIGRCNKAGKPIICATQMLE--SMIKKPRPTRAEGSDV 349

  Fly   372 ---FLWKVDAIHIQKSPWCNKYPL-IVKKLMPIKDYRVGAVQNKMVLK-----SILTSYQTIVNF 427
               .|...|.|.:........||| .|:....|......|..::.:.:     |:||...:....
Zfish   350 ANAVLDGADCIMLSGETAKGDYPLEAVRTQHMIAREAEAATFHRQLFEGLRRSSVLTRDPSDAVA 414

  Fly   428 IIRTISSIECQA--IFLFTTCETASVALSRIEIYCPVYVMVPLEETDDAETITCKVELARALHLR 490
            :....:|.:|.|  |.:.|....::..:||.....|:..:...|:|            ||..||.
Zfish   415 VGAVEASFKCCASGIIILTKTGRSAHLISRYRPRAPILAVTRNEQT------------ARQAHLY 467

  Fly   491 RNMHPVLYTKDLNECSYSPIE----FGVDFMRKKGCLEVGDFVVTL 532
            |.:.|:.|....|:.....::    |.:|..:.:|..:.||.|:.|
Zfish   468 RGIFPIYYNSPSNDVWAEDVDLRVNFAMDVGKARGFFKAGDVVIVL 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12229	NP_648980.1	pyruv_kin	103..530	CDD:273424	104/471 (22%)
		Pyruvate_Kinase	126..530	CDD:304951	101/448 (23%)
pkma	NP_955365.1	Pyruvate_Kinase	43..531	CDD:238178	111/501 (22%)
		pyruv_kin	44..528	CDD:273424	111/501 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11817
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010