Protein Alignment CG12229 and LOC1275938

DIOPT Version :10

• Sequence 1: NP_648980.1
• Gene: CG12229 / 39945
• FlyBaseID: FBgn0036723
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: XP_061506259.1
• Gene: LOC1275938 / 1275938
• VectorBaseID: AGAMI1_009609
• Length: 727
• Species: Anopheles gambiae
• Alignment Length: 491
• Identity: 109/491 - (22%)
• Similarity: 209/491 - (42%)
• Gaps: 90/491 - (18%)

  Fly    91 RRMLENGTYTFHVDTVGNKPDELKAILDTMNIAISAHSAERELRLTTGLALEINGECCRVGRLRN 155
            |....:|::.:|.:|:.|           :..|:..:|.:........:||:..|...|.|.:..
Mosquito   267 RLNFSHGSHEYHANTIKN-----------IREAVDNYSKKLGKPFPLAIALDTKGPEIRTGLIEG 320

  Fly   156 NCT--VMLARGGVVTLTTDESYRYKGFKEIVYV--INLRCYLASVQLGDIVMIGREVRGKVVKTL 216
            :.|  |.|.:|..:.||||:.:..||.|:.:||  :|:   :..|:.||.|.:...:...||:::
Mosquito   321 SGTGEVELKKGEKIQLTTDKEHLEKGTKDKIYVDYVNI---VKVVKPGDHVFVDDGLISLVVESI 382

  Fly   217 R-EALTVMIIDAGLVASYDFIELPRQCHALDPDLYPDLYMK---DLEMAASLNANYVVLPKIRCK 277
            . :.||..:.:.|::.|...:.||    .:..|| |.:..|   ||........:.:....||..
Mosquito   383 SGDTLTCTVENGGMLGSRKGVNLP----GVPVDL-PAVSEKDKSDLAFGVEQGVDVIFASFIRNA 442

  Fly   278 SFLRAVRQTL-NSDFNLKLIGMIDFEYVRSNMLDLLGIIKLVDYIWIP--DMFNVNCCVYNYIME 339
            :.|:.:|..| ....::|:|..|:.:   ..|.:|..||:..|.|.:.  |: .:........:.
Mosquito   443 AALKEIRTILGEKGKHIKIISKIENQ---QGMQNLDKIIEATDGIMVARGDL-GIEIPAEKVFLA 503

  Fly   340 DVLPISQCQK--KPVI-GTVPLERCSDFK-----RFELHD----FLWKVDAIHIQKSPWCNKYPL 392
            ....|::|.:  |||| .|..||  |..|     |.|:.|    .:...|.:.:.......:|||
Mosquito   504 QKSMIARCNRAGKPVICATQMLE--SMIKKPRPTRAEISDVANAIIDGADCVMLSGETAKGEYPL 566

  Fly   393 --IVKKLMPIKDYRVGAVQNKMVLKSILTSYQTIVNFIIRTISSI-----------ECQAIFLFT 444
              ::......|:.. .|:.::.:.|.::.:..|.::    |.:||           ...||.:.|
Mosquito   567 ECVLTMAKTCKEAE-AALWHRNLFKDLVDTTPTPLD----TAASIAIAGAEASIKSRAAAIIVIT 626

  Fly   445 TCETASVALSRIEIYCPVYVMVPLEETDDAETITCKVELARALHLRRNMHPVLY--------TKD 501
            |...::..:|:....||:..:....:|            ||..||.|.:.||:|        .||
Mosquito   627 TSGRSAHLISKYRPRCPIIAVTRFAQT------------ARQCHLYRGILPVIYEQPAMEDWLKD 679

  Fly   502 LNECSYSPIEFGVDFMRKKGCLEVGDFVVTLEVGKE 537
            ::    :.:::|::|.:::|.|:.|:.:|.:...|:
Mosquito   680 VD----ARVQYGIEFGKERGFLKPGNPIVVVTGWKQ 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12229	NP_648980.1	Pyruvate_Kinase	126..530	CDD:453956	101/447 (23%)
LOC1275938	XP_061506259.1	None