Protein Alignment CG12229 and pklr

DIOPT Version :10

• Sequence 1: NP_648980.1
• Gene: CG12229 / 39945
• FlyBaseID: FBgn0036723
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: NP_958446.1
• Gene: pklr / 114551
• ZFINID: ZDB-GENE-010907-1
• Length: 538
• Species: Danio rerio
• Alignment Length: 497
• Identity: 103/497 - (20%)
• Similarity: 180/497 - (36%)
• Gaps: 111/497 - (22%)

  Fly    91 RRMLENGTYTFHVDTVGNKPDELKAILDTMN--------IAISAHSAERELRLTTGLALEINGEC 147
            |....:||:.:|.:|:.|    ::..::|:.        :||:..:...|:|  |||   :.|
Zfish    79 RLNFSHGTHQYHAETIRN----VREAVETLTSDPLYYRPVAIALDTKGPEIR--TGL---VKG-- 132

  Fly   148 CRVGRLRNNCTVMLARGGVVTLTTDESYR-----------YKGFKEI------VYVINLRCYLAS 195
                  |.:..|.|.||.:|.:.|.|..|           |.....:      :|:.:....|..
Zfish   133 ------RADAEVTLERGALVRVVTAECEREQTDGSVIWMDYPSLTRVLKKDSRIYIDDGLLALRV 191

  Fly   196 VQLGDIVMIGREVRGKVVKTLREALTVMIIDAGLVASYDFIELPRQCHALDPDLYPDLYMKDLEM 260
            :::||..:..|...|                 |::.|...:.|| ....||.....:....||:.
Zfish   192 LEIGDSWLQARVENG-----------------GVLGSSKGVNLP-GAELLDLPAVSERDRSDLQF 238

  Fly   261 AASLNANYVVLPKIRCKSFLRAVRQTLN-SDFNLKLI-------GMIDFEYVRSNMLDL------ 311
            ......:.:....|||...:||||..|. ...::|:|       |:.:||.|......:
Zfish   239 GVEQQVDMIFASFIRCAEDVRAVRDALGPQGHDIKIISKVESRQGVRNFEQVLQESDGVMVARGD 303

  Fly   312 LGIIKLVDYIWIPDMFNVNCCVYNYIMEDVLPISQCQKKPVIGTVPLERCSDFKRFELHD----F 372
            |||....:.::|.....:..|  |...:.|:..:|..:..|....|       .|.|..|    .
Zfish   304 LGIEIPAEKVFIAQKMMIGRC--NSAGKPVICATQMLESMVHHARP-------TRAESSDVANAV 359

  Fly   373 LWKVDAIHIQKSPWCNKYPL-IVKKLMPIKDYRVGAVQNKMVLKSI-----LTSYQTIVNFIIRT 431
            |...|.:.:........:|: .|..:..|......|:.::.:.:.:     |:|..|.|..|...
Zfish   360 LDGADCVMLSGETAKGHFPVEAVAMMHSICREAEAAIFHQQLFEELRRLTPLSSDPTEVTAIGAV 424

  Fly   432 ISSIEC--QAIFLFTTCETASVALSRIEIYCPVYVMVPLEETDDAETITCKVELARALHLRRNMH 494
            .||.:|  .||.:.||...::..|||....||:.            .:|...::||...|.|.:.
Zfish   425 ESSYKCCAGAIIILTTSGRSAQLLSRYRPRCPII------------AVTRNAQVARQSQLLRGVF 477

  Fly   495 PVLYTKDLNECSYSPIE----FGVDFMRKKGCLEVGDFVVTL 532
            |.|:.....|.....::    |.:|..:.:|....||.|:.:
Zfish   478 PALFRAPPAEVWADDVDNRVTFAMDIGKARGFFRSGDMVIVV 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12229	NP_648980.1	Pyruvate_Kinase	126..530	CDD:453956	93/450 (21%)
pklr	NP_958446.1	Pyruvate_Kinase	48..537	CDD:238178	103/497 (21%)