DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32176 and CAAP1

DIOPT Version :9

Sequence 1:	NP_730271.1	Gene:	CG32176 / 39944	FlyBaseID:	FBgn0052176	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_079104.3	Gene:	CAAP1 / 79886	HGNCID:	25834	Length:	361	Species:	Homo sapiens

Alignment Length:	240	Identity:	58/240 - (24%)
Similarity:	100/240 - (41%)	Gaps:	67/240 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 LHPMSHYIDDRLELVKQIFGTLKPKTILNLAPEFLKKTPLDEIEELCLEELLCLSTKRLKSIIEN 96
            |.|:|.||.|:.|:::|.|..:..|.:..:.|:.||...::||::||.|:|..||.|::..|:|.
Human   133 LKPVSFYISDKKEMLQQCFCIIGEKKLQKMLPDVLKNCSIEEIKKLCQEQLELLSEKKILKILEG 197

  Fly    97 TKCPTDTESSEDSDVEHKEEH--------ISLEEISSDSDIGGQESRKTKKKLRSKKTNNGNENK 153
                   ::..|||:|.:.:.        :|.::|..||          ...:|..|...|.|.|
Human   198 -------DNGMDSDMEEEADDGSKMGSDLVSQQDICIDS----------ASSVRENKQPEGLELK 245

  Fly   154 ESGGQMSVLELLELQARARAIRSQLAMEPITKIEVKSDDDID----------EVPVEKVQRK--- 205
            :..|:.|  ::|.:.|.|                  .|.||:          |.|...||.:
Human   246 QGKGEDS--DVLSINADA------------------YDSDIEGPCNEEAAAPEAPENTVQSEAGQ 290

  Fly   206 ----EKD-KRSTKK----TDSSKRKSQESARPTSPSQPDSSSKEQ 241
                ||| ::|..:    .:||..:.:.:.....|.:....|.:|
Human   291 IDDLEKDIEKSVNEILGLAESSPNEPKAATLAVPPPEDVQPSAQQ 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32176	NP_730271.1	CAAP1	33..94	CDD:291980	21/60 (35%)
CG32176	NP_730271.1	SPATA3	199..>296	CDD:292290	11/55 (20%)
CAAP1	NP_079104.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	67..100
		CAAP1	134..195	CDD:291980	21/60 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	198..218		4/19 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	230..331		24/120 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145602
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_29F4A
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006909
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR14740
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	6	5.890