DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32176 and Caap1

DIOPT Version :9

Sequence 1:	NP_730271.1	Gene:	CG32176 / 39944	FlyBaseID:	FBgn0052176	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_080644.2	Gene:	Caap1 / 67770	MGIID:	1915020	Length:	356	Species:	Mus musculus

Alignment Length:	265	Identity:	62/265 - (23%)
Similarity:	110/265 - (41%)	Gaps:	66/265 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 SIKKEKIEEER------------KLHPMSHYIDDRLELVKQIFGTLKPKTILNLAPEFLKKTPLD 72
            |::||....|.            .|.|:|.||.|:.|:::|.|..:..|.:..:.|:.||...::
Mouse    89 SLEKELFLAEHSDLEEGGLDLNVSLKPVSFYISDKKEMLQQCFCIIGEKKLQKMLPDVLKNCSVE 153

  Fly    73 EIEELCLEELLCLSTKRLKSIIENTKCPTDTESSEDSDVEHKEEH--------ISLEEISSDSDI 129
            ||::||.|:|..||.|::..|:|.       ::..|||:|.:.:.        ||.::...||
Mouse   154 EIKKLCQEQLELLSEKQILKILEG-------DNGLDSDMEEEADDGCKVAPDLISQQDTCVDS-- 209

  Fly   130 GGQESRKTKKKLRSKKTNNGNENKESGGQMSVLELLELQARA-----------RAIRSQLAMEPI 183
                    ...||..|.....|:|:..|:.|  ::|.:.|.|           .|..:..|....
Mouse   210 --------TSSLRENKQPEVLESKQGKGEDS--DVLSINADAYDSDIEGPSIDEAAAAATATPAA 264

  Fly   184 TKIEVKSDDDIDEVPVEKVQRK-------EKD-KRSTKK----TDSSKRKSQESARPTSPSQPDS 236
            |.:...:    .|||...||.:       |:| ::|..:    .:||.::.:.:.....|::...
Mouse   265 TAVATAA----SEVPENTVQSEAGQIDDLERDIEKSVNEILGLAESSPKEPKVATLTVPPAEDVQ 325

  Fly   237 SSKEQ 241
            .|.:|
Mouse   326 PSAQQ 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32176	NP_730271.1	CAAP1	33..94	CDD:291980	21/60 (35%)
CG32176	NP_730271.1	SPATA3	199..>296	CDD:292290	10/55 (18%)
Caap1	NP_080644.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	54..80
		CAAP1	114..175	CDD:291980	21/60 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	208..234		9/37 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835668
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_29F4A
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006909
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR14740
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.890