DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment frc and Slc35d3

DIOPT Version :9

Sequence 1:	NP_001137962.1	Gene:	frc / 39943	FlyBaseID:	FBgn0042641	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_083805.1	Gene:	Slc35d3 / 76157	MGIID:	1923407	Length:	422	Species:	Mus musculus

Alignment Length:	322	Identity:	95/322 - (29%)
Similarity:	155/322 - (48%)	Gaps:	26/322 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 IGSALFYGLSSFMITVVNKTVLTSYHFPSFLFLSLGQ-LTASIVVLGMG--KRLKLVNFPP---- 121
            |..|:.:|:.|..:.::.|.:::.|.|.   ||:|.| ||:|...|.:.  :||.|:..||
Mouse    12 ISVAIAHGVFSGSLNILLKFLISRYQFS---FLTLVQCLTSSTAALSLELLRRLGLIAVPPFGLS 73

  Fly   122 LQRNTFAKIFPLPLIFLGNMMFGLGGTKTLSLPMFAALRRFSILMTMLLELKIL-GLRPSNAVQV 185
            |.| :||.:..|..:.....::.|.|   |||||:...:|...|:|||:.:.:| ...||..|..
Mouse    74 LAR-SFAGVAVLSTLQSSLTLWSLRG---LSLPMYVVFKRCLPLVTMLIGVLVLKNGAPSPGVLA 134

  Fly   186 SVYAMIGGALLAASDDLSFNMRGYIYVMITNALTASNGVYVKKKLDTSEIGKYGLMYYNSLFMFL 250
            :|.....||.||.:.||:.:..||:..::...:.|:..|.::|....:|.|.....|..:: ...
Mouse   135 AVLITTCGAALAGAGDLTGDPIGYVTGVLAVLVHAAYLVLIQKASADTEHGPLTAQYVIAV-SAT 198

  Fly   251 PALAL-NYVTGNLDQALNFEQWND----SVFVVQFLLSCVMGFILSYSTILCTQFNSALTTTIVG 310
            |.|.: ::.:.:...|..|..|.|    |:||...|:.|.|.|    :|:.||..|||:||:.||
Mouse   199 PLLVICSFASTDSIHAWTFPGWKDPAMVSIFVACILIGCAMNF----TTLHCTYINSAVTTSFVG 259

  Fly   311 CLKNICVTYLGMFIGGDYVFSWLNCIGINISVLASLLYTYVTFRRKRAPDKQDHLPS-TRGE 371
            .:|:|....:||....|...:.|...|:.::.|.|::|....|...|.....:.|.| ..||
Mouse   260 VVKSIATITVGMVAFSDVEPTSLFIAGVVVNTLGSIIYCVAKFLETRRQSNYEDLESQAEGE 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
frc	NP_001137962.1	TPT	67..348	CDD:281186	87/293 (30%)
Slc35d3	NP_083805.1	VRG4	30..308	CDD:227402	87/289 (30%)
Slc35d3	NP_083805.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	339..365
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5070
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55087
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820