DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment frc and Slc35d1

DIOPT Version :9

Sequence 1:	NP_001137962.1	Gene:	frc / 39943	FlyBaseID:	FBgn0042641	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	XP_038965467.1	Gene:	Slc35d1 / 298280	RGDID:	1309843	Length:	405	Species:	Rattus norvegicus

Alignment Length:	310	Identity:	169/310 - (54%)
Similarity:	230/310 - (74%)	Gaps:	9/310 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 SKELSHREREDSAL--------FVKKIGSALFYGLSSFMITVVNKTVLTSYHFPSFLFLSLGQLT 102
            :|..:||:.|:..:        |:|.: :|.|||:|||:|.||||:|||:|.|||.|.:.|||:.
  Rat    18 AKSSTHRDEEELGMAPAETLTVFLKLL-AAGFYGVSSFLIVVVNKSVLTNYRFPSSLCVGLGQMV 81

  Fly   103 ASIVVLGMGKRLKLVNFPPLQRNTFAKIFPLPLIFLGNMMFGLGGTKTLSLPMFAALRRFSILMT 167
            |::.||.:||.|::|.||...||...|.|||||::.||.:.||..||.|:||||..|||||||.|
  Rat    82 ATVAVLWVGKALRVVKFPDFDRNVPRKTFPLPLLYFGNQITGLFSTKKLNLPMFTVLRRFSILFT 146

  Fly   168 MLLELKILGLRPSNAVQVSVYAMIGGALLAASDDLSFNMRGYIYVMITNALTASNGVYVKKKLDT 232
            |..|..:|....|..::::|:|||.||.:|||.||:|::.||::::|.:.|||:||.|||:|||:
  Rat   147 MFAEGALLKKTFSWGIKMTVFAMIIGAFIAASSDLAFDLEGYVFILINDVLTAANGAYVKQKLDS 211

  Fly   233 SEIGKYGLMYYNSLFMFLPALALNYVTGNLDQALNFEQWNDSVFVVQFLLSCVMGFILSYSTILC 297
            .|:|||||:|||:|||.||.||:.|.||:..:|:.||.|.|::|::||.|||||||||.|:|:||
  Rat   212 KELGKYGLLYYNALFMILPTLAIAYFTGDAQKAMEFEGWADALFLLQFTLSCVMGFILMYATVLC 276

  Fly   298 TQFNSALTTTIVGCLKNICVTYLGMFIGGDYVFSWLNCIGINISVLASLL 347
            ||:|||||||||||:|||.:||:||..||||:|:|.|.||:|||.|...|
  Rat   277 TQYNSALTTTIVGCIKNILITYIGMVFGGDYIFTWTNFIGLNISCLLGTL 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
frc	NP_001137962.1	TPT	67..348	CDD:281186	163/281 (58%)
Slc35d1	XP_038965467.1	VRG4	49..327	CDD:227402	161/278 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	341	1.000	Domainoid score	I1048
eggNOG	1	0.900	-	-		E1_COG5070
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22870
Inparanoid	1	1.050	358	1.000	Inparanoid score	I2149
OMA	1	1.010	-	-		QHG55087
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002341
OrthoInspector	1	1.000	-	-		oto97085
orthoMCL	1	0.900	-	-		OOG6_102424
Panther	1	1.100	-	-	LDO	PTHR11132
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1771
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.830