DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment frc and sqv-7

DIOPT Version :9

Sequence 1:	NP_001137962.1	Gene:	frc / 39943	FlyBaseID:	FBgn0042641	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_495436.1	Gene:	sqv-7 / 174145	WormBaseID:	WBGene00005025	Length:	329	Species:	Caenorhabditis elegans

Alignment Length:	309	Identity:	165/309 - (53%)
Similarity:	217/309 - (70%)	Gaps:	4/309 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 KIGSALFYGLSSFMITVVNKTVLTSYHFPSFLFLSLGQLTASIVVLGMGKRLKLVNFPPLQRNTF 127
            ::.||:|||:.|.:|..|||.:||:|.||||||:.:||:.|:|::|...|..::|.||.|..:..
Worm    12 RVFSAVFYGVISVLIVFVNKILLTNYKFPSFLFVGVGQMMATILILFFAKMFRIVQFPSLDSSIP 76

  Fly   128 AKIFPLPLIFLGNMMFGLGGTKTLSLPMFAALRRFSILMTMLLELKILGLRPSNAVQVSVYAMIG 192
            .||.||||::..|::.|||||:.::||||..||||||||||:||..||.::.|.||::||..|||
Worm    77 RKIMPLPLLYFFNLISGLGGTQMINLPMFTVLRRFSILMTMILEFYILNVKASKAVKISVGLMIG 141

  Fly   193 GALLAASDDLSFNMRGYIYVMITNALTASNGVYVKKKLDTSEIGKYGLMYYNSLFMFLPALALNY 257
            |:.:||..||||:..||..:.|.|..||:.|||.|:|||..::||||||:||.|||.||||.:..
Worm   142 GSFIAAIYDLSFDALGYTMIFINNICTAALGVYTKQKLDAKDLGKYGLMFYNCLFMLLPALCVVQ 206

  Fly   258 VTGNLDQALNF---EQWNDSVFVVQFLLSCVMGFILSYSTILCTQFNSALTTTIVGCLKNICVTY 319
            .||:||:|.:|   :....||:.. |||||:.||:|:||.:|||..|||||||.||.:||:.|||
Worm   207 YTGDLDRAYSFMLSDSMTSSVWTC-FLLSCICGFVLNYSLVLCTHHNSALTTTCVGPIKNLFVTY 270

  Fly   320 LGMFIGGDYVFSWLNCIGINISVLASLLYTYVTFRRKRAPDKQDHLPST 368
            :|||..|||||.|.|..|||:||..|:||||||||.|........||.|
Worm   271 VGMFSSGDYVFQWANFTGINVSVFGSILYTYVTFRSKSTTISYKPLPMT 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
frc	NP_001137962.1	TPT	67..348	CDD:281186	152/283 (54%)
sqv-7	NP_495436.1	TPT	21..299	CDD:281186	148/278 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166524
Domainoid	1	1.000	297	1.000	Domainoid score	I793
eggNOG	1	0.900	-	-		E1_COG5070
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22870
Inparanoid	1	1.050	324	1.000	Inparanoid score	I1472
Isobase	1	0.950	-	0	Normalized mean entropy	S1931
OMA	1	1.010	-	-		QHG55087
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002341
OrthoInspector	1	1.000	-	-		oto20631
orthoMCL	1	0.900	-	-		OOG6_102424
Panther	1	1.100	-	-	LDO	PTHR11132
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R503
SonicParanoid	1	1.000	-	-		X1771
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.780