DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sec3 and Stxbp6

DIOPT Version :9

Sequence 1:	NP_648976.2	Gene:	Sec3 / 39940	FlyBaseID:	FBgn0266669	Length:	889	Species:	Drosophila melanogaster
Sequence 2:	NP_001178801.1	Gene:	Stxbp6 / 362734	RGDID:	1306117	Length:	210	Species:	Rattus norvegicus

Alignment Length:	212	Identity:	55/212 - (25%)
Similarity:	92/212 - (43%)	Gaps:	47/212 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 KHTLQKELFLASGERLLSVVTVVKKKDKK-P-----------CYLCV-VTTAPPVPVVTLCLIKQ 62
            |..:.||:|....||:|..|.|.::..|| |           .|:|: ||...|    |...|.:
  Rat     4 KSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSVTNKKP----TQASITK 64

  Fly    63 SEQREG--EYKRKRSWQLDEIKWVDGRNEQFETHEFDLQLEKLY-KWYALNPHERQNFLAVLNRQ 124
            .:|.||  .:.|:..|.|::::.|:|.:...::.||||..|..: :|.|....|:..|..:|:..
  Rat    65 VKQFEGSTSFVRRSQWMLEQLRQVNGIDPNRDSAEFDLLFENAFDQWVASTASEKCTFFQILHHT 129

  Fly   125 IQKSVRGQRAEFRNVPAAWLS----------------EKSPEKV-----ALGRAVQKTQHMDDEE 168
            .|:.:..::.||.|..:..:.                :|:.:.:     .||||.:||      |
  Rat   130 CQRYLTDRKPEFINCQSKIMGGNSILHSAADSVTSAVQKASQALNERGERLGRAEEKT------E 188

  Fly   169 DEEEEAQEFTALTDKEA 185
            |.:..||:|.....|.|
  Rat   189 DMKNSAQQFAETAHKLA 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sec3	NP_648976.2	PH-EXOC1	9..126	CDD:270202	37/130 (28%)
Sec3	NP_648976.2	Sec3_C	200..866	CDD:286804
Stxbp6	NP_001178801.1	PH-STXBP6	2..131	CDD:270200	37/130 (28%)
Stxbp6	NP_001178801.1	R-SNARE_STXBP6	149..210	CDD:277245	14/63 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334918
Domainoid	1	1.000	41	1.000	Domainoid score	I12202
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D201698at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940