Protein Alignment Sec3 and STXBP6

DIOPT Version :9

• Sequence 1: NP_648976.2
• Gene: Sec3 / 39940
• FlyBaseID: FBgn0266669
• Length: 889
• Species: Drosophila melanogaster
• Sequence 2: XP_016876721.1
• Gene: STXBP6 / 29091
• HGNCID: 19666
• Length: 222
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 55/212 - (25%)
• Similarity: 92/212 - (43%)
• Gaps: 47/212 - (22%)

  Fly    11 KHTLQKELFLASGERLLSVVTVVKKKDKK-P-----------CYLCV-VTTAPPVPVVTLCLIKQ 62
            |..:.||:|....||:|..|.|.::..|| |           .|:|: ||...|    |...|.:
Human    16 KSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSVTNKKP----TQASITK 76

  Fly    63 SEQREG--EYKRKRSWQLDEIKWVDGRNEQFETHEFDLQLEKLY-KWYALNPHERQNFLAVLNRQ 124
            .:|.||  .:.|:..|.|::::.|:|.:...::.||||..|..: :|.|....|:..|..:|:..
Human    77 VKQFEGSTSFVRRSQWMLEQLRQVNGIDPNGDSAEFDLLFENAFDQWVASTASEKCTFFQILHHT 141

  Fly   125 IQKSVRGQRAEFRNVPAAWLS----------------EKSPEKV-----ALGRAVQKTQHMDDEE 168
            .|:.:..::.||.|..:..:.                :|:.:.:     .||||.:||      |
Human   142 CQRYLTDRKPEFINCQSKIMGGNSILHSAADSVTSAVQKASQALNERGERLGRAEEKT------E 200

  Fly   169 DEEEEAQEFTALTDKEA 185
            |.:..||:|.....|.|
Human   201 DLKNSAQQFAETAHKLA 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec3	NP_648976.2	PH-EXOC1	9..126	CDD:270202	37/130 (28%)
		Sec3_C	200..866	CDD:286804
STXBP6	XP_016876721.1	PH-STXBP6	14..143	CDD:270200	37/130 (28%)
		R-SNARE_STXBP6	161..222	CDD:277245	14/63 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141252
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D201698at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850