Protein Alignment blot and Slc6a2

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_112633.2
• Gene: Slc6a2 / 83511
• RGDID: 621822
• Length: 617
• Species: Rattus norvegicus
• Alignment Length: 560
• Identity: 133/560 - (23%)
• Similarity: 213/560 - (38%)
• Gaps: 144/560 - (25%)

  Fly   233 ANVVRFPRELDRY------GSAYLVPYVVLLFLVGLPMVLLEISVGQFLGQGAAHTWRASPIFKG 291
            |||.|||     |      |.|:|:||.:.|.:.|:|:..:|:::|||..:|||..|:..|.|||
  Rat    77 ANVWRFP-----YLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQFNREGAATVWKICPFFKG 136

  Fly   292 ACMISRFASWLSAIWVSL--QAVLALAYIGMFAS--NDLPFR---------ECAGPVKLRLS--- 340
            .    .:|..|.|::|..  ..::|.:...:|||  .:||:.         .|..|..|..|
  Rat   137 V----GYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNCGHAWNSPNCTDPKLLNASVLG 197

  Fly   341 -------------------GYL-LTGTSGQE-----------CLQLTFLTPFWRNPLYF----GL 370
                               |.| |..:||..           ||.:..:.      |||    |:
  Rat   198 DHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVIVV------LYFSLWKGV 256

  Fly   371 LAAGLIGLWIVVMLCTHNAKILRRSIFVFGLVGLVLLCTLTGWEVRNSFSRHYFPELWGFDSNLL 435
            ..:|.: :||...|          ..||. .|.||...||.|  ..|..:.:..     .|...|
  Rat   257 KTSGKV-VWITATL----------PYFVL-FVLLVHGVTLPG--ASNGINAYLH-----IDFYRL 302

  Fly   436 AESNIWFNALMQVLFSVNCGFGALPMIT--GKF---LYKGDAVRTSVVYLCFNLLINAIAVTLFM 495
            .|:.:|.:|..|:.||:..|||.|....  .||   .|: ||:.||.:. |....|:..|:
  Rat   303 KEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYR-DALLTSTIN-CVTSFISGFAI---- 361

  Fly   496 VQFDLSSNGFQNMEELKPLTAIYDRVLNGS-------REGDSHLLQHLVPSLIYALIILS----- 548
                .|..|:...|.   ...|.|....|:       .|..|.|......::::.|::|:
  Rat   362 ----FSILGYMAHEH---KVKIEDVATEGAGLVFVLYPEAISTLSGSTFWAVLFFLMLLALGLDS 419

  Fly   549 ---AMVSITVAVYTSTRLVPRRPNYVICLIGL---VVAVISFAAPKFLIARVLDSRLVGTMVVTA 607
               .|.::...:....:::.|......|.:.|   ::|:.........:..:||:...||.::.|
  Rat   420 SMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLTLLDTFAAGTSILFA 484

  Fly   608 LVFELIAITWIYGAKNIYTDLEFSIGRPIFRVWMWLW-VICPAILTGILVW-------WCADDDQ 664
            ::.|.|.::|.||......|::..:|......|...| .:.||.|..::|.       ...||..
  Rat   485 VLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYV 549

  Fly   665 YDLLAEYLPRWAPILFVLAVIVIIACVQIFRQVEYNFFGM 704
            |       |.||.  :|...|.:.:.:.:...|.|.||.:
  Rat   550 Y-------PPWAN--WVGWGIALSSMILVPAYVIYKFFSI 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	121/513 (24%)
Slc6a2	NP_112633.2	SLC5-6-like_sbd	56..615	CDD:382020	133/560 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810