Protein Alignment blot and Slc6a19

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_083154.1
• Gene: Slc6a19 / 74338
• MGIID: 1921588
• Length: 634
• Species: Mus musculus
• Alignment Length: 602
• Identity: 133/602 - (22%)
• Similarity: 239/602 - (39%)
• Gaps: 144/602 - (23%)

  Fly   222 LVLCLCLNLSYANVVRFPRELDRY-GSAYLVPYVVLLFLVGLPMVLLEISVGQFLGQGAAHTWRA 285
            ::.|:...:...||.|||.....: |.|:::|:::||...|:|::.||.::||.|.:|:...|.:
Mouse    42 MLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVFEGIPLLYLEFAIGQRLRKGSMGVWSS 106

  Fly   286 -SPIFKGACMISRFASWLSAIWVSLQAVLALAYIGMFASNDLPFRECAGPVKLRLSGYLLTGTSG 349
             .|..||..:.|.|.|::..::.:......:.|........||:.||  |:....:||:
Mouse   107 IHPALKGIGIASMFVSFMVGLYYNTIIAWVMWYFFNSFQEPLPWSEC--PLNQNQTGYV------ 163

  Fly   350 QECLQLTFLTPFW-RNPLYF--GLLAAGLIGLWIVVML-CTHNAK---ILR------RSIFVFGL 401
            :||.:.:.:..|| |..|..  .:..:|.|..||::.| |..:..   |:|      :::::...
Mouse   164 EECAKSSSVDYFWYRETLNISTSISDSGSIQWWILLCLTCAWSVLYVCIIRGIETTGKAVYITST 228

  Fly   402 VGLVLL-------CTLTGWEVRNSFSRHYFPELWGFDSNLLAESNIWFNALMQVLFSVNCGFGAL 459
            :..|:|       .||.|  ..|.....:.|.:     ..|:..|.|.:|..||.:|.:..||.|
Mouse   229 LPYVVLTIFLIRGLTLKG--ATNGIVFLFTPNI-----TELSNPNTWLDAGAQVFYSFSLAFGGL 286

  Fly   460 PMITGKFLYKGDAVRTSVVYLCFNLLINAIAVTLF--MVQFDLSS--------------NGF--- 505
            ...:.......:....||:....|...:..|.|:.  ::.|..:.              |||
Mouse   287 ISFSSYNSVHNNCEMDSVIVSVINGFTSVYAATVVYSIIGFRATERFDDCVNTNILTLINGFDLP 351

  Fly   506 ------QNME---------------ELKPLTAIYDRVLNGSREGDSHLLQHLV-----------P 538
                  :|.|               :||..|...:..|:...||..  |..:|           |
Mouse   352 EGNVTSENFEAYQQWCNATNPQAYAQLKFQTCDINSFLSEGVEGTG--LAFIVFTEAITKMPVSP 414

  Fly   539 --SLIYALII----LSAM---VSITVAVYTSTRLVPRR-PNY----VICL-IGLVVAVISFAAPK 588
              |:::.:::    ||:|   :...|.......:.|:: |..    :||| ..|:..:.:..:.:
Mouse   415 LWSVLFFIMLFCLGLSSMFGNMEGVVVPLQDLNITPKKWPKELLTGLICLGTYLIAFIFTLNSGQ 479

  Fly   589 FLIARVLDSRLVGTMVVTALVF-ELIAITWIYGAKNIYTDLEFSIGRPIFRVWMWLW-VICPAIL 651
            :.:: :||| ..|::.:..:.| |:.|:.::||......|:||.||......|...| |:.|.|:
Mouse   480 YWLS-LLDS-FAGSIPLLIIAFCEMFAVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLIM 542

  Fly   652 TGILVW--------------WCADDDQYDLLAEY-------LPRWAPILFVLAVIVIIA---CVQ 692
            ..|.::              |   |..|:   |:       .|.|     |.||:|.:|   |:.
Mouse   543 LVIFLFFFVIEVNKTLMYSIW---DPNYE---EFPKSQKIPYPNW-----VYAVVVTVAGVPCLS 596

  Fly   693 IFRQVEYNFFGMICEAS 709
            |.....|.|....|:.|
Mouse   597 IPCFAIYKFIRNCCQKS 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	116/540 (21%)
Slc6a19	NP_083154.1	SLC5-6-like_sbd	32..612	CDD:294310	132/599 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000