Protein Alignment blot and slc6a4b

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_001170930.1
• Gene: slc6a4b / 664770
• ZFINID: ZDB-GENE-060314-2
• Length: 591
• Species: Danio rerio
• Alignment Length: 616
• Identity: 136/616 - (22%)
• Similarity: 241/616 - (39%)
• Gaps: 151/616 - (24%)

  Fly   199 NAKLLPA-VEDES-NKQTKCSVFRGLVLCLCLNLSYANVVRFPRELDRY------GSAYLVPYVV 255
            |:..:|. ::.|| :|.:|...|...|:...::|  .||.|||     |      |.|:|:|||:
Zfish    25 NSNPVPVIIQTESRDKWSKKMDFLLSVIGFAVDL--GNVWRFP-----YICYQNGGGAFLIPYVL 82

  Fly   256 LLFLVGLPMVLLEISVGQFLGQGAAHTWR-ASPIFKGACMISRFASWLSAIWVSL--QAVLALAY 317
            :....|:|:..:|:::|||...||...|: ..|||||.    .||..:.|::||.  ..::|.|.
Zfish    83 MAVFGGVPLFYMELALGQFHRTGAISIWKHICPIFKGI----GFAICIIALYVSFYYNTIIAWAL 143

  Fly   318 IGMFA--SNDLPFREC------------AGPVKLRLSGYLLT-------------------GTSG 349
            ...::  |:.||:..|            .|...:..:.|..:                   |..|
Zfish   144 FYFYSSFSSTLPWTSCDNDWNTENCTNYFGKDNVTWTNYSRSPAEEFYTRNVLAVHESSGLGNVG 208

  Fly   350 ------QECLQLTFLTPFWRNPLYFGLLAAGLIGLWIVVMLCTHNAKILRRSIFVFGLVGLVLLC 408
                  ..||.|.|...::  .|:.|:..:|.: :|:...|           .:|..|:.::...
Zfish   209 YIRWQLMLCLFLIFTIVYF--SLWKGVKTSGKV-VWVTATL-----------PYVVLLILMIRGA 259

  Fly   409 TLTG-WE--VRNSFSRHYFPELWGFDSNLLAESNIWFNALMQVLFSVNCGFGALPMITGKFLYKG 470
            ||.| |:  |      .|....|    ..|.|:::|.:|..|:.||:..|||.|..::....:..
Zfish   260 TLPGAWKGVV------FYLNPKW----EKLKETSVWVDAAAQIFFSLGPGFGVLLALSSYNPFTN 314

  Fly   471 DAVRTSVVYLCFNLLINAIA-VTLFMVQFDLSSNGFQNMEELKPLTAIYDRVLNGSREGDSHL-- 532
            :..|.::|....|.|.:.:: ..:|.|...::.....|:|::            ...:|.|.|
Zfish   315 NCYRDAIVTSLVNCLTSFVSGFVIFTVLGYMAEQRNVNVEDV------------ARDKGPSLLFI 367

  Fly   533 -----LQHLVPSLIYALIILSAMVSITV--------AVYTSTR------LVPRRPNY-----VIC 573
                 :.::|.|..:|:|....|:::.:        |:.|:..      |..||..:     |:|
Zfish   368 TYPEAIANMVGSTFFAIIFFVMMITLGLDSTFGGLEAIITAVMDEYPDVLSHRRELFVLGLVVVC 432

  Fly   574 LIGLVVAVISFAAPKFLIARVLDSRLVGTMVVTALVFELIAITWIYGAKNIYTDLEFSIGRPIFR 638
            .:|.:..:....|   .:.::|:...||:.::..:..|..|::|.||......|::..:|.....
Zfish   433 FLGSLSTLTKGGA---YVVKLLEEFGVGSSIIAIVFLEATAVSWFYGINRFSNDIKSMLGYTPGL 494

  Fly   639 VWMWLWV-ICPAILTGILVWWCADDDQYDLLAEYLPRWAPILFVLAVIVIIACVQIFRQVEYNFF 702
            .|...|| |.||.|..|::....:.....|.....|.|:     :.|..||..........|..:
Zfish   495 FWKVCWVAISPAFLAYIIISSLLNPQTLTLFDYEFPDWS-----ITVGYIIGASSFIWIPIYMVY 554

  Fly   703 GMICEASKPAKEWGPADPLARHSWKQWRSVC 733
            .::         |.|.      |.||..:||
Zfish   555 KLV---------WTPG------SLKQRLAVC 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	116/518 (22%)
slc6a4b	NP_001170930.1	SLC6sbd_SERT	38..574	CDD:271399	132/603 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900