Protein Alignment blot and slc6a7

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: XP_005161359.1
• Gene: slc6a7 / 562050
• ZFINID: ZDB-GENE-070112-1492
• Length: 652
• Species: Danio rerio
• Alignment Length: 621
• Identity: 134/621 - (21%)
• Similarity: 228/621 - (36%)
• Gaps: 151/621 - (24%)

  Fly   154 SGIVTLSDSNNTLSEIQGGYHDMDHDAVSKNFSISASAHNITTASNAKLLPAVEDESNKQTKCSV 218
            :|::|...:.|...:         :.|||.  .:::.:...::|::....|..:....|
Zfish    30 NGVITTPSTENPAHQ---------NGAVSS--PVASQSQPPSSAASPPAQPPRDQWGGK------ 77

  Fly   219 FRGLVLCLCLNLSYANVVRFPRELDRY-GSAYLVPYVVLLFLVGLPMVLLEISVGQFLGQGAAHT 282
            :..|:.|:...:...||.|||....|. |..:|:||.::||..|:|:.|:|:|:||:...|....
Zfish    78 YEFLLSCIGYCVGLGNVWRFPYLCYRNGGGVFLIPYFIMLFFTGMPLFLMELSLGQYGAAGPITV 142

  Fly   283 WRASPIFKGACMISRFASWLSAIWVSLQAVLALAYIGMFASNDLPFRECAGPVKLRLSGYLLTGT 347
            |:..|:.||..:.....|.|..::.::.......|:|....:.||: .|.....:.|
Zfish   143 WKCCPLLKGIGIGMLCVSTLVCLYYNVIIAWTFYYLGSSFQSPLPW-SCDALQNIAL-------- 198

  Fly   348 SGQECLQLTFLTP-----FW-------------------RNPLYFGLLAAGLIGLWIVVMLCTHN 388
                |...|..|.     ||                   |.||...||||     ||::.||
Zfish   199 ----CANKTNSTQSPSEVFWNEKVLGVVHSTGLSDPGPVRWPLALCLLAA-----WIIIFLC--- 251

  Fly   389 AKILRRSIFVFGLVGLV---------LLCTLTGWEVRNSFS--RHYFPELWGFDSNLLAESNIWF 442
               :.:.|...|.|..|         |:..:.|..:..|..  ..|....|    :.||::.:|.
Zfish   252 ---MLKGIHSSGKVVYVTATFPYFVLLVLIIRGATLEGSLDGVAFYLTPKW----DQLADAQVWN 309

  Fly   443 NALMQVLFSVNCGFGALPMITGKFLYKGDAVRTSVVYLCFNLLINAIAVTLFMVQFDL-SSNGFQ 506
            :|..|:.:|:..|.|.|..:.....:..:.:|.:::....|      ..|.|...|.: |..|..
Zfish   310 DAASQIFYSLGIGVGGLLSMASYNKFDNNVIRDTIIITIGN------CSTSFFAGFAIFSILGHM 368

  Fly   507 NMEELKPLTAIYD--------------RVLNGSREGDSHLLQHLVPSLIYALI--------ILSA 549
            ..::..|:..:.|              .:|.||          :..|:::.|:        :...
Zfish   369 AFKKGVPVDKVADSGPGLAFVAYPEALALLPGS----------VFWSILFFLMLFMLGVDTLFGN 423

  Fly   550 MVSITVAVYTSTRLVPR-RPNYVICLIGLVVAVISFAAPKFLIA--------RVLD--SRLVGTM 603
            |..|..||...   .|: |.|.....:.|.|...||.....|:.        .::|  |...|.:
Zfish   424 MEGICTAVLDE---FPQLRSNLKHKTLFLAVLCFSFYLMGLLLITDGGIYWFTLIDSFSTSFGLI 485

  Fly   604 VVTALVFELIAITWIYGAKNIYTDLEFSIGR-PIFRVWMWL-----WVI-CPAILTGILVWWCAD 661
            ::|  :|..|.|::.||......|:...|.| |.:...|.|     ||: .|.:||.||.:...
Zfish   486 IIT--LFMCIGISFFYGVNQFCQDIVDMICRCPPWCTKMLLYFKACWVVFTPFLLTFILTYIFI- 547

  Fly   662 DDQYDLLAEY----LPRWAPILFVLAVIVIIACVQI 693
             :.|.....|    .|.|...|.|  .:..:.|:||
Zfish   548 -EMYRTSLRYGSYVYPIWGKALGV--CMGALCCLQI 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	116/516 (22%)
slc6a7	XP_005161359.1	SLC5-6-like_sbd	71..610	CDD:294310	126/569 (22%)
		PotE	<235..564	CDD:223605	79/366 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900