Protein Alignment blot and slc6a19a.1

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_001091648.1
• Gene: slc6a19a.1 / 553256
• ZFINID: ZDB-GENE-070620-2
• Length: 629
• Species: Danio rerio
• Alignment Length: 574
• Identity: 133/574 - (23%)
• Similarity: 234/574 - (40%)
• Gaps: 137/574 - (23%)

  Fly   222 LVLCLCLNLSYANVVRFPRELDRY-GSAYLVPYVVLLFLVGLPMVLLEISVGQFLGQGAAHTWRA 285
            ::.|:...:...||.|||.....: |.|:::|:::||.|.|:|::.||.::||.|..|:...||:
Zfish    41 MLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGVPLLHLEFAIGQRLRSGSVGVWRS 105

  Fly   286 -SPIFKGACMISRFASWLSAIWVSLQAVLALAYIGMFASNDLPFRECAGPVKLRLSGYLLTGTSG 349
             ||...|..:.|..||::..::.:......:.|:.......||:.:|  ||.|..:|.:
Zfish   106 ISPYLTGVGIASMLASFIVGMYYNTIMAWVMWYLFNSLQEPLPWSQC--PVNLNRTGLV------ 162

  Fly   350 QECLQLTFLTPFW-RNPL--YFGLLAAGLIGLWIVVML----------CTHNAKILRRSIFVFGL 401
            .||.:.:.:..|| |..|  ...:..:|.:..|:|:.|          |....:...:::::...
Zfish   163 SECERSSPVDYFWYRETLNTSTAIEDSGALQWWLVLCLLCAWTFLYICCIRGIETTGKAVYITST 227

  Fly   402 VGLVLL-------CTLTGWEVRNSFSRHYFPELWGFDSNLLAESNIWFNALMQVLFSVNCGFGAL 459
            :..|:|       .||.|       |.:....|:..|.|.|...:.|.:|..|||||.:..||.|
Zfish   228 LPYVVLTIFLIRALTLKG-------SVNGIKFLFTPDVNELMNPSTWLDAGAQVLFSFSLAFGGL 285

  Fly   460 PMITGKFLYKG-------DAVRTS------------VVY------------LCFN----LLINAI 489
            ...:.   |..       |||..|            |:|            :|.:    .|:||.
Zfish   286 ISFSS---YNSVHNNCEQDAVTISIINGLTSVYSATVIYSIIGFRATENYDICLDSNILSLLNAF 347

  Fly   490 AV----------TLFMVQFDLSSNGFQNMEELKPLTAIYDRVLNGSREGDSHLLQHLV------- 537
            .:          |:.:.|.::|....  ::||:..|.....:|:...||..  |..:|
Zfish   348 DLPEGSITENNYTVALQQLNISRPDI--IQELQLKTCDMQTLLSEGVEGTG--LAFIVFTEAITK 408

  Fly   538 ----P--SLIYALII----LSAM---VSITVAVYTSTRLVPRR-PNYVI----CLIGLVVAVISF 584
                |  |:::.:::    ||.|   :...|.......|:|:| |..|.    |::..:.|::..
Zfish   409 MPVSPLWSVLFFIMLFCLGLSTMFGNIEGVVVPLQDLNLLPKRWPKEVFTGLTCVVSFLTALVFV 473

  Fly   585 -AAPKFLIARVLDSRLVGT--MVVTALVFELIAITWIYGAKNIYTDLEFSIGRPIFRVWMWLW-V 645
             ::..:.:|  |.....|:  ::|.||. ||||:.::||......|::|.:|......|...| .
Zfish   474 QSSGNYWLA--LFDGFAGSIPLLVIALC-ELIAVVYVYGIDRFNEDIKFMVGHKPNIFWQISWRF 535

  Fly   646 ICPAILTGILVW--------------WCADDDQYDLLAEY-LPRW-APILFVLA 683
            :.|.||..||::              |......:..|.|. .|.| :.::||||
Zfish   536 LSPVILLVILIFYFITTVSKQLTYNVWDPQSADFPTLKEVDYPNWISVVIFVLA 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	124/546 (23%)
slc6a19a.1	NP_001091648.1	SLC5-6-like_sbd	31..611	CDD:294310	133/574 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.000