Protein Alignment blot and SLC6A15

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_877499.1
• Gene: SLC6A15 / 55117
• HGNCID: 13621
• Length: 730
• Species: Homo sapiens
• Alignment Length: 614
• Identity: 126/614 - (20%)
• Similarity: 233/614 - (37%)
• Gaps: 131/614 - (21%)

  Fly   206 VEDESNKQTKCSVFRGLVLCLCLNLSYANVVRFPRELDRY-GSAYLVPYVVLLFLVGLPMVLLEI 269
            ||||  :....|..:.::..:..::...||.|||....:. |.|||:||::||.::|:|:..||:
Human    57 VEDE--RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLEL 119

  Fly   270 SVGQFLGQGAAHTWR-ASPIFKGACMISRFASWLSAIWVSLQAVLALAYIGMFASNDLPFRECAG 333
            ||||.:.:|:...|. .||...|....|....:..|::.::....:|.|........||:.:|
Human   120 SVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWDQC-- 182

  Fly   334 PVKLRLSGYLLTGTSGQECLQLTFLTPFW-RNPLYF--------GL---LAAGLIGLWIVVMLC- 385
            |:....|...:.    .||.|.:..|.:| |..|..        ||   :...|:..|::|.|.
Human   183 PLVKNASHTFVE----PECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVCLAM 243

  Fly   386 ----THNAKILR-RSIFVFGLVGLVLLCTL-TGWEVRNSFS--RHYF-PELWGFDSNLLAESNIW 441
                ..:.||:. .|:|.:    :||:|.| ..:.:..|..  ||.| |:|     .::.|..:|
Human   244 IKGIQSSGKIIYFSSLFPY----VVLICFLIRAFLLNGSIDGIRHMFTPKL-----EIMLEPKVW 299

  Fly   442 FNALMQVLFSVNCGFGAL----------------PMITGKFLYKGDAVRTSVVYLCFNLLINAI- 489
            ..|..||.|::..|||.:                .::.....:....:.|.||:.......|.|
Human   300 REAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANVIN 364

  Fly   490 ---------AVTLFMVQFDLSSNGFQNMEELKPLTA-----IYDRV------------------- 521
                     .:..|:...::|.:...:...|..:||     :||.:
Human   365 EKCITQNSETIMKFLKMGNISQDIIPHHINLSTVTAEDYHLVYDIIQKVKEEEFPALHLNSCKIE 429

  Fly   522 --LNGSREGD-------SHLLQHLVPSLIYALIILSAMVS------------ITVAVYTSTRLVP 565
              ||.:.:|.       :..:.|...|..::::....:|:            |...:..:.::..
Human   430 EELNKAVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIVTPIVDTFKVRK 494

  Fly   566 RRPNYVICLIGLVVAVISFAAPKFLIARVLDSRLVGTMVVTALVFELIAITWIYGAKNIYTDLEF 630
            .....:.||:...:.:|...........:.|.......::..::.|.||:.::||......||:.
Human   495 EILTVICCLLAFCIGLIFVQRSGNYFVTMFDDYSATLPLLIVVILENIAVCFVYGIDKFMEDLKD 559

  Fly   631 SIGRPIFRVWMWLW-VICPAILTGILV--------------WWCADDDQYDLLAEYLPRWAPILF 680
            .:|....|.:.::| .|.|.:|..:|:              .|..|....:.|:  .|.|..::.
Human   560 MLGFAPSRYYYYMWKYISPLMLLSLLIASVVNMGLSPPGYNAWIEDKASEEFLS--YPTWGLVVC 622

  Fly   681 VLAVIVIIACVQIFRQVEYNFFGMICEAS 709
            |..|:..|..|.:...|..  |.:|.::|
Human   623 VSLVVFAILPVPVVFIVRR--FNLIDDSS 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	108/549 (20%)
SLC6A15	NP_877499.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	41..60		2/2 (100%)
		SLC6sbd_SBAT1	61..640	CDD:212091	118/595 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910