Protein Alignment blot and SLC6A20

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_001372612.1
• Gene: SLC6A20 / 54716
• HGNCID: 30927
• Length: 603
• Species: Homo sapiens
• Alignment Length: 618
• Identity: 137/618 - (22%)
• Similarity: 237/618 - (38%)
• Gaps: 152/618 - (24%)

  Fly   225 CLCLNLSYANVVRFPRELDRY-GSAYLVPYVVLLFLVGLPMVLLEISVGQFLGQGAAHTWRA-SP 287
            |:...:...||.|||.....| |.::||||:::|.:.|:|::.||::|||.:.||:...||. ||
Human    18 CISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISP 82

  Fly   288 IFKGACMISRFASWLSAIWVSLQAVLALAYIGMFASNDLPFRECAGPVKLRLSGYLLTGTSGQEC 352
            ...|..:.|...|:..:::.::....|..|:.....:.||:..|  |:....:||      .:||
Human    83 YLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWSVC--PLNGNHTGY------DEEC 139

  Fly   353 LQLTFLTPFWR------------------NPLYFGLLAAGLIGLWIVVMLCTHNAKILRRS---- 395
            .:.:....||.                  .|....|||      |:||.||     |||.:
Human   140 EKASSTQYFWYRKTLNISPSLQENGGVQWEPALCLLLA------WLVVYLC-----ILRGTESTG 193

  Fly   396 ---IFVFGLVGLVLL------CTLTGWEVRNSFSRHYFPE------LWGFDSNLLAESNIWFNAL 445
               .|...|...||:      .||.|  ..|.....:.|:      |..|....||....|.||.
Human   194 KVVYFTASLPYCVLIIYLIRGLTLHG--ATNGLMYMFTPKGSSALSLLAFQIEQLANPKAWINAA 256

  Fly   446 MQVLFSVNCGFGALPMITGKFLYKGDAVRTSVVYLCFNLLINAIA-------------------- 490
            .|:.||:..|||:|...........:..:.:::....|...:..|
Human   257 TQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTSIFASIVTFSIYGFKATFNYENCL 321

  Fly   491 --VTLFMVQ-FDLSSNGF---QNMEELKPLTA---------IYDRVLNGSREGD----------- 529
              |:|.:.. ||| .:||   .|:|::|...|         ::.::.|.|.|.:
Human   322 KKVSLLLTNTFDL-EDGFLTASNLEQVKGYLASAYPSKYSEMFPQIKNCSLESELDTAVQGTGLA 385

  Fly   530 ----SHLLQHLVPSLIYALII--------LSAMVSITVAVYT--------STRLVPRRPNYVICL 574
                :..::::..|.:::::.        :.:|:..|.|:.|        |:.|.....:.::||
Human   386 FIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTDSKIISSHLPKEAISGLVCL 450

  Fly   575 IGLVVA-VISFAAPKFLIARVLDSRLVGTMVVTALVFELIAITWIYGAKNIYTDLEFSIGRPIFR 638
            :...:. |.:..|..:......|.....::::..|| |.||:.::||.:...:||:...||.:..
Human   451 VNCAIGMVFTMEAGNYWFDIFNDYAATLSLLLIVLV-ETIAVCYVYGLRRFESDLKAMTGRAVSW 514

  Fly   639 VWMWLWV-ICPA-------------ILTGILVWWCADDDQYDLLAEYLPRWAPILFVLAVIVIIA 689
            .|..:|. :.|.             ||||.|.:...|..|..|:.:..|.:|..:..|.|.....
Human   515 YWKVMWAGVSPLLIVSLFVFYLSDYILTGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTM 579

  Fly   690 CVQIFRQVEYNFFGMICEASKPAKEWGPADPLA 722
            |:.:.....:        ..:..|. |.|||:|
Human   580 CIPLAALGTF--------VQRRLKR-GDADPVA 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	123/553 (22%)
SLC6A20	NP_001372612.1	SLC6sbd_SIT1	2..588	CDD:271401	131/592 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910