Protein Alignment blot and Slc6a12

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_059031.1
• Gene: Slc6a12 / 50676
• RGDID: 620255
• Length: 628
• Species: Rattus norvegicus
• Alignment Length: 566
• Identity: 125/566 - (22%)
• Similarity: 211/566 - (37%)
• Gaps: 167/566 - (29%)

  Fly   230 LSYANVVRFPRELDRY------GSAYLVPYVVLLFLVGLPMVLLEISVGQFLGQGAAHTWR-ASP 287
            :...||.|||     |      |.|:.:||.:..|..|:|:..||:::||:..||:...|| ..|
  Rat    68 IGLGNVWRFP-----YLCYKNGGGAFFIPYFIFFFSCGIPVFFLEVALGQYSSQGSVTAWRKICP 127

  Fly   288 IFKGACMIS-RFASWLSAIWVSLQAVLALAYIGMFASN--DLPFRECAGPVKLRLSGYLLTGTSG 349
            :.:|..|.| ...|:|:..::   .:||.|...:|:|.  :||:..|.            ...:.
  Rat   128 LLQGIGMASVVIESYLNIYYI---IILAWALFYLFSSFTWELPWTTCT------------NSWNT 177

  Fly   350 QECLQL-------------TFLTP---FWRNPLYFGL-------------LAAGLIGLWIVVMLC 385
            :.|:..             .|.:|   ||...: .|:             ||..|:..||:...|
  Rat   178 EHCVDFLNYSSTRAASYSENFTSPVMEFWERRV-LGITSGIHDLGSLRWELALCLLLAWIICYFC 241

  Fly   386 T-HNAKILRRSIF---VFGLVGLVLLCTLTGWEVRNSFSRHYF---PELWGFDSNLLAESNIWFN 443
            . ...|...:.::   .|..:.|::| .:.|..:..::....|   |:|.     .|.:..:|.:
  Rat   242 IWKGVKSTGKVVYFTATFPYLMLIIL-LIRGVTLPGAYQGIVFYLKPDLL-----RLKDPQVWMD 300

  Fly   444 ALMQVLFSVNCGFGALPMITGKFLYKGDAVRTSVVYLCFNLLINAIAVTLFMVQFDL-SSNGFQN 507
            |..|:.||.....|.|..:.....|..:..|.|:. |||   :|  :.|.|:..|.: |..||..
  Rat   301 AGTQIFFSFAICQGCLTALGSYNKYHNNCYRDSIA-LCF---LN--SATSFVAGFVVFSILGFMA 359

  Fly   508 MEELKPLTAIYDRVLNGSREGDSHL----------LQHLVPSLIYALIIL----SAMVSITVAVY 558
            .|:..|::.:.:     |..|.:.:          |..|...|.:.:::.    |..|.:...|.
  Rat   360 QEQGVPISEVAE-----SGPGLAFIAFPKAVTMMPLSQLWSCLFFLMLLFLGLDSQFVCMECLVT 419

  Fly   559 TSTRLVP-------RRPNYVICLIGLVVAVISFAAPKFLIARVLDSRLVGTMVVTAL-------- 608
            .|..:.|       ||.     |:.|.||::.:.....|:..       |.|.:..|
  Rat   420 ASMDMFPQQLRKRGRRE-----LLILAVAIVCYLMGLLLVTE-------GGMYIFQLFDYYASSG 472

  Fly   609 -------VFELIAITWIYGAKNIYTDLEFSIGRPIFRVW-----MWLWV---ICPAILTGILVWW 658
                   :||:|.|.|:|||...|.::|..||   :|.|     .||::   :|.|..
  Rat   473 ICLLFLSLFEVICIGWVYGADRFYDNVEDMIG---YRPWPLVKISWLFLTPGLCLATF------- 527

  Fly   659 CADDDQYDLLAEY----------LPRWAPILFVLAVIVIIACVQIF 694
                  :..|::|          .|.|...:..|.....:|||.:|
  Rat   528 ------FFSLSKYTPLKYNNVYIYPSWGYSIGWLLAFSSMACVPLF 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	116/519 (22%)
Slc6a12	NP_059031.1	SLC5-6-like_sbd	49..589	CDD:294310	125/566 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900