Protein Alignment blot and slc6a1b

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_001007363.1
• Gene: slc6a1b / 492490
• ZFINID: ZDB-GENE-041114-57
• Length: 600
• Species: Danio rerio
• Alignment Length: 590
• Identity: 135/590 - (22%)
• Similarity: 228/590 - (38%)
• Gaps: 120/590 - (20%)

  Fly   146 ATSGRISSSGIV--------TLSDSNNTLSEIQGGYHDMDHDAVSKNFSISASAHNITTASNAKL 202
            ||:|..:|.|.|        |.:|...||                           :......|.
Zfish     2 ATNGTKASDGHVLTEVNEAPTANDKPKTL---------------------------VVKVQKKKE 39

  Fly   203 LPAVEDESNKQTKCSVFRGLVLCLCLNLSYANVVRFPRELDRY-GSAYLVPYVVLLFLVGLPMVL 266
            ||      :::|....|..|:.|:...:...||.|||....:. |.|:|:||.:.|...|:|:..
Zfish    40 LP------DRETWQGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFF 98

  Fly   267 LEISVGQFLGQGAAHTWRASPIFKGACMISRFAS-WLSAIWVSLQAVLALAYIGMFASNDLPFRE 330
            ||.::||:...|....|:.:|:|||..:.:...| ||:..::.:.| .|:.|:....:.|||::.
Zfish    99 LETALGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIIA-WAIYYLYNSFTTDLPWKS 162

  Fly   331 CAGP--VKLRLSGYLLTGTSGQECLQLTFLTPFW-RN--PLYFGLLAAGLIGL---------WIV 381
            |..|  .....|.|.:.....    ..:.:..|| ||  .|..||...|.|.|         |::
Zfish   163 CDNPWNTDKCFSNYSMANIGN----MTSAVVEFWERNMHQLTDGLEKPGEIRLPLAITLAIAWVL 223

  Fly   382 VMLCT-----HNAKILRRS-------IFVFGLVGLVLLCTLTGWEVRNSFSRHYFPELWGFDSNL 434
            |..|.     ...|::..|       :|:..:.|:    ||.|  .:.....:..||.     :.
Zfish   224 VYFCIWKGVGWTGKVVYFSATYPYFMLFILFIRGV----TLPG--AKEGILFYVTPEF-----SK 277

  Fly   435 LAESNIWFNALMQVLFSVNCGFGALPMITGKFLYKGDAVRTSVVYLCFNLLINAIAVTLFMVQFD 499
            |.||.:|.:|..|:.||...|.|:|..:.....:..:..:.|::..|.|...:..|.  |::
Zfish   278 LKESEVWLDAATQIFFSYGLGLGSLIALGSYNPFNNNVYKDSIIVCCINSFTSMFAG--FVI--- 337

  Fly   500 LSSNGFQNMEELKPLTAIYDRVLNGSREGDSHL-----LQHLVPSLIYALIILSAMVSI------ 553
            .|..||......:|:..:     ..|..|.:.|     :..|..|.::|::..|.::.:
Zfish   338 FSIVGFMAHITKRPIADV-----AASGPGLAFLAYPEAVTQLPISPLWAVLFFSMLLMLGIDSQF 397

  Fly   554 -TVAVYTSTRLVPRRPN----------YVICLIGLVVAVISFAAPKFLIARVLDSRLVGTMVVTA 607
             ||..:. |.||...|.          .|:||:..::.:.:.......:.::.|......|.:..
Zfish   398 CTVEGFI-TALVDEFPRALRGRREIFIAVVCLVSYLIGLSNITQGGLYVFKLFDYYSASGMCLLF 461

  Fly   608 LV-FELIAITWIYGAKNIYTDLEFSIGRPIFRVWMWLWVI-CPAILTGILVWWCADDDQYDLLAE 670
            || ||.::|:|.||....|.:||..||......|...||: .|.|:.|:.::.........|...
Zfish   462 LVFFECVSISWFYGVNKFYGNLEEMIGYKPCIWWKLCWVVFTPLIVAGVFLFSAVQMVPLTLNNY 526

  Fly   671 YLPRW 675
            ..|:|
Zfish   527 VFPKW 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	118/491 (24%)
slc6a1b	NP_001007363.1	SLC5-6-like_sbd	2..600	CDD:294310	135/590 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810