Protein Alignment blot and Slc6a16

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_001311464.1
• Gene: Slc6a16 / 381884
• MGIID: 2685930
• Length: 742
• Species: Mus musculus
• Alignment Length: 750
• Identity: 152/750 - (20%)
• Similarity: 265/750 - (35%)
• Gaps: 224/750 - (29%)

  Fly   106 MRRAKANETDLPTVTPSPQTTRSCISTVSSVVDSGGGRTTATSGRISSS---------GIVTLSD 161
            ||..|..|.:       |..:|:..|.|....:|....:.:...:::..         |::|.|.
Mouse     1 MRSTKEGENE-------PSKSRASPSDVPQASESNMEESVSWDSKLTDMDSHLGAWEVGMLTWSP 58

  Fly   162 SNNTLSEIQGGYHDMDHDAVSKNFSISASAHNITTASNAKLLP-----------AVEDESN---- 211
            | ..:::.|          ||:.....|.|......:...|.|           .:|.||:
Mouse    59 S-TWIAQAQ----------VSETRMAKAQAWETLALARITLQPKPSVTELATVTTLEQESSELVN 112

  Fly   212 ------------KQTKCSVFRGLVLCLCLNLSYANVVRFPRELDRYGS-AYLVPYVVLLFLVGLP 263
                        :|...|....::..:...|..:.|:||.......|| ::.:.|:::|..:|:|
Mouse   113 RMSRESSEGYPPRQLWASKVEYMLAIMSYLLMPSGVLRFASGWVHKGSCSFFIAYILMLLGIGIP 177

  Fly   264 MVLLEISVGQFLGQGAAHTWR-ASPIFKG-------ACMISR-----FASWLSAIWVSLQAVLAL 315
            ::.||::|||...|.:|..|: .||.|.|       .|.|:.     |.||:         :..:
Mouse   178 LLFLEMAVGQRAQQSSADMWKNLSPWFGGVGYSMVMVCFITNTYLNVFNSWI---------LFYM 233

  Fly   316 AYIGMFASNDLPFRECAGPVKLRLSGYLLTGTSGQECLQLTFLTPFW-RNPL------------Y 367
            ::|..|.   :|:.:|  |::...|.:      ..||.|.|..|.|| |..|            .
Mouse   234 SHIFYFV---VPWDQC--PLQRNSSNF------DPECEQATSYTYFWYRKTLKASDRIEDGGQPS 287

  Fly   368 FGLLAAGLIGLWIVVMLCTHNAKILRRSIFVFGLVGL-VLLC------TLTGWEVRNSFSRHYFP 425
            |.|..:..:...::.....:..|.:.:.:||..||.. :::|      ::.|.|
Mouse   288 FSLGMSLFLSFCLICAFLVNGIKSIGKVLFVLLLVPYSIIVCFLIRTLSMDGAE----------- 341

  Fly   426 ELWGFDSNL------LAESNIWFNALMQVLFSVNCGFGALPMITGKFLYKGDAVRTSVVYLCFNL 484
              :|....|      :::..||.:|.:||||.:..|||.:..:........:.:..:.:...|.:
Mouse   342 --YGLKHLLILKVASISDLTIWCHAGIQVLFDIGLGFGPIVSLASHVPDFNNCMADAFLMALFKI 404

  Fly   485 LINAIAVTLFM-VQFDLSSNGF-----------QNMEELKPLTA-------IYDRVLNGSREGD- 529
                  :||.| ..|.||..||           :|.|.|..|.|       .....|:|:...:
Mouse   405 ------ITLLMTTPFLLSILGFWATTTTHHCCKKNQETLLRLVAQGILPPDAQPPDLSGNPTSNY 463

  Fly   530 SHLLQHLVPSLIYAL----------------------------------------IILSAMVSIT 554
            :..|..|.|.|..|:                                        |:|..::.:|
Mouse   464 NSWLSSLPPPLRSAVLSVVPECSVQKQFLKIKDNPRFLFLIFTEVISLLPGSGFWIVLFFLLLLT 528

  Fly   555 VA-----------VYTSTRLVP---RRPNYVICLIGLVVAV--ISFAAPK-FLIARVLDSRLVGT 602
            :.           |.|.....|   |:|..:|..:.:.:.:  :.|..|. .....:|....|..
Mouse   529 LGLCSNLMFMLGNVLTLQDTFPFCRRQPRLLIVCVSMAMFLCGLIFIQPSGIYYFSLLSECWVAV 593

  Fly   603 MVVTALVFELIAITWIYGAKNIYTDLEFSIGRPIFRVWMWLW-VICPAILTGI------------ 654
            .|:..::.|.:|:.|.|||.....|:...:|||||....||| .|.|.::.|:
Mouse   594 PVIIIIICENLAVAWAYGADRFLADMVALLGRPIFSGCGWLWCYISPMVVLGLLTSVFVYLVKGP 658

  Fly   655 LVWWCADDDQYDLLAEYLPRWAPILFV-LAVIVII 688
            ||::..|......:....|.|:.||.. |.|.|::
Mouse   659 LVYFAWDSSTSKEVVRVFPEWSKILIAGLTVFVLM 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	119/569 (21%)
Slc6a16	NP_001311464.1	SLC5-6-like_sbd	125..694	CDD:294310	129/607 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100