Protein Alignment blot and DAT

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Alignment Length: 652
• Identity: 143/652 - (21%)
• Similarity: 243/652 - (37%)
• Gaps: 219/652 - (33%)

  Fly   174 HDMDHDAVSKNFSISASAHNITTASNAKLLPAVEDESNKQTKCSVFRGLVLCLCLNLSYANVVRF 238
            ||.|::::|                         ||  ::|.......|:..:...:..|||.||
  Fly    16 HDNDNNSIS-------------------------DE--RETWSGKVDFLLSVIGFAVDLANVWRF 53

  Fly   239 PRELDRY------GSAYLVPYVVLLFLVGLPMVLLEISVGQFLGQGAAHTW-RASPIFKGACMIS 296
            |     |      |.|:||||.::|.:.|:|:..:|:::||...:||...| |..|:|||.
  Fly    54 P-----YLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGI---- 109

  Fly   297 RFASWLSAIWVSL--QAVLALAYIGMFAS--NDLPFREC-------------------------- 331
            .:|..|.|.:|..  ..::|.:....|||  |.||:..|
  Fly   110 GYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFESQNASRVPVIGNY 174

  Fly   332 -----AGPVKLRLSGYLLTGTS---------------GQE------------------------- 351
                 .|...|..:...:.|:|               ..|
  Fly   175 SDLYAMGNQSLLYNETYMNGSSLDTSAVGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDM 239

  Fly   352 --CLQLTFLTPFWRNPLYFGLLAAGLIGLWIVVMLCTHNAKILRRSIFVFGLVGLVLL--CTLTG 412
              ||.:.:|..::  .|:.|:..:|.: :|..             ::|.:.::.::|:  .||.|
  Fly   240 ALCLLIVYLICYF--SLWKGISTSGKV-VWFT-------------ALFPYAVLLILLIRGLTLPG 288

  Fly   413 ------WEVRNSFSRHYFPELWGFDSNLLAESNIWFNALMQVLFSVNCGFGALPMIT--GKF--- 466
                  :.:..:||..|             ::.:|.:|..||.||:..|||.|....  .|:
  Fly   289 SFLGIQYYLTPNFSAIY-------------KAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNN 340

  Fly   467 LYKGDAVRTSVV---------YLCFNLLINAIAVTLFMVQFDLSSNGFQNMEELKP--LTAIYDR 520
            :|| ||:.||.:         ::.|::| ..:|.||.:...|:::.|        |  :..:|..
  Fly   341 VYK-DALLTSFINSATSFIAGFVIFSVL-GYMAHTLGVRIEDVATEG--------PGLVFVVYPA 395

  Fly   521 VLNGSREGDSHLLQHLVPSLIYALIILSAMVSI--------TVAVYTS-----TRLVPRRPNYVI 572
            .           :..:..|..:|||....::::        :.|:.|:     .::...|..:|.
  Fly   396 A-----------IATMPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVA 449

  Fly   573 CLIGL--VVAVISFAAPKFLIARVLDSRLVGTMVVTALVFELIAITWIYGAKNIYTDLEFSIGRP 635
            .|..|  ||.:.|.....|....:||....|..::.|:.||.||::||||......|:...||.|
  Fly   450 GLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFP 514

  Fly   636 IFRVWMWLW-VICPAILTGILVWWCADDDQYDLL--AEYL-PRWAPIL---FVLAVIVIIACVQI 693
            ..|.|...| .:.|..|..|.|:....   |:.|  |:|: |.||..|   ...:.:|:|..|.|
  Fly   515 PGRYWQVCWRFVAPIFLLFITVYGLIG---YEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAI 576

  Fly   694 FR 695
            |:
  Fly   577 FK 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	123/563 (22%)
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	137/614 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910