Protein Alignment blot and Slc6a14

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: XP_038955501.1
• Gene: Slc6a14 / 298340
• RGDID: 1561810
• Length: 646
• Species: Rattus norvegicus
• Alignment Length: 683
• Identity: 151/683 - (22%)
• Similarity: 255/683 - (37%)
• Gaps: 183/683 - (26%)

  Fly   187 ISASAHNITTASNAKLLPAVEDESNKQTKCSVFRGLVLCLCLNLSYA----NVVRFPRELDRY-- 245
            ::||:.|.....|        ||:.::...|.....:|.:   :.||    ||.|||     |
  Rat    24 VTASSENFHVGEN--------DENQERGNWSKKSDYLLSM---VGYAVGLGNVWRFP-----YLT 72

  Fly   246 ----GSAYLVPYVVLLFLVGLPMVLLEISVGQFLGQGAAHTWRASPIFKGA----CMISRFASWL 302
                |.|:|:||.::|.|.|||:..||.|:|||...|....||..|:|:|.    .:||.|
  Rat    73 YTNGGGAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVWRILPLFQGVGITMVLISIF---- 133

  Fly   303 SAIWVSLQAVLALAYIGMFAS--NDLPFRECAG----------PV--KLRLSGYLLTGTSGQECL 353
              :.:....::|.:...:|||  :.||:..|:.          |:  ..|:|    |.|.|.
  Rat   134 --VTIYYNVIIAYSLYYLFASFQSVLPWANCSSSWADDNCSRQPIVTGCRVS----TDTGGD--- 189

  Fly   354 QLTFLTPFWRNPLYFGLLAAGLIGLWIVVMLCTHNAKI----------------LRRS------- 395
              .|:...|.|...|               .|.:.:::                ||||
  Rat   190 --MFMNISWVNSNNF---------------TCLNGSEVFRPGQLPSEQYWDKVTLRRSSGMDETG 237

  Fly   396 IFVFGLVGLVLLCTLTGW---------EVRNSFSRHYFPELW----------------------- 428
            :.|:.|.    ||.|..|         .:::|....||..|:
  Rat   238 VIVWYLA----LCLLLAWIIVGAALFKGIKSSGKVVYFTALFPYVVLLILLIRGATLEGASKGIS 298

  Fly   429 ---GFDSNL--LAESNIWFNALMQVLFSVNCGFGALPMITGKFLYKGDAVRTSVVYLCFNLLINA 488
               |..||.  |.|:.:|.:|..|:.:|::..:|.|..::....:..:....:::....|.|.:.
  Rat   299 YYIGAQSNFTKLREAEVWKDAATQIFYSLSVAWGGLVALSSYNKFNNNCYSDAIIVCLTNCLTSV 363

  Fly   489 IA-VTLFMVQFDLSSNGFQNMEELKPLTAIYDRVLNGSREGDSHLLQHLVPSLIYALIIL----- 547
            .| ..:|.:...::.  ....|..:.:.:.:|.......|..:.|......|:::..::|
  Rat   364 FAGFAIFSILGHMAH--ISGKEVSQVVKSGFDLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLD 426

  Fly   548 SAMVSITVAVYTSTRLVPRRPNYV-------ICLIGLVVAVISFAAPKFLIARVLDSRLVGTMVV 605
            |...||.....|...|.|:....:       .|||..::.::...........::|....|..::
  Rat   427 SQFASIETITTTIQDLFPKAMKRMRVPITLGCCLILFLLGLVCVTQAGIYWVHLIDHFCAGWGIL 491

  Fly   606 TALVFELIAITWIYGAKNIYTDLEFSIGRPIFRVWMW---LW-VICPAILTGILVWWCADDDQYD 666
            .|.:.|:..|.||||......|:|..||...:..|:|   .| ||.|.:|:.||||        .
  Rat   492 IAAILEIAGIIWIYGGNRFIEDIEMMIGAKRWLFWLWWRACWFVITPILLSAILVW--------S 548

  Fly   667 LLAEYLPR--------------WAPILFVLAVIVIIACVQIFRQVEYNFFGMICEASKPAKEWGP 717
            |:..:.|.              |..|:|.:..|.|:|.::|.| .|.|....|.:..:||..|||
  Rat   549 LVKFHRPNYADIPYPDWGVALGWCMIIFCIIWIPIMAIIKIVR-AEGNILQRIIKCCRPASNWGP 612

  Fly   718 ADPLARHSWKQWRSVCQDTGRRDFTLRR-RGTR 749
            .  |.:|..::::.:.:.....|..:.. .|||
  Rat   613 Y--LEKHRGERYKDMAEPAKETDHEIPTISGTR 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	120/544 (22%)
Slc6a14	XP_038955501.1	SLC6sbd_ATB0	42..645	CDD:271391	145/657 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810