Protein Alignment blot and Slc6a6

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: XP_008761345.1
• Gene: Slc6a6 / 29464
• RGDID: 61912
• Length: 631
• Species: Rattus norvegicus
• Alignment Length: 566
• Identity: 131/566 - (23%)
• Similarity: 212/566 - (37%)
• Gaps: 171/566 - (30%)

  Fly   234 NVVRFPRELDRY------GSAYLVPYVVLLFLVGLPMVLLEISVGQFLGQGAAHTW-RASPIFKG 291
            ||.|||     |      |.|:|:||.:.||..|||:..||:.:||:..:|....| :..|:|.|
  Rat    73 NVWRFP-----YLCYKNGGGAFLIPYFIFLFGSGLPVFFLEVIIGQYTSEGGITCWEKICPLFSG 132

  Fly   292 ACMISRFASWLSAIWVSLQ-----AVLALAYIGMFAS--NDLPFRECAGPVKLRLSGYLLTGTSG 349
                   ..:.|.:.|||.     .:||.|...:|.|  .|||:..|.            ...:.
  Rat   133 -------IGYASIVIVSLLNVYYIVILAWATYYLFQSFQKDLPWAHCN------------HSWNT 178

  Fly   350 QECLQLT---------------FLTP---FW-RNPLYF--GL---------LAAGLIGLWIVVML 384
            .:|::.|               |.:|   || ||.|..  |:         ||..|:.:|:|...
  Rat   179 PQCMEDTLRRNESHWVSLSAANFTSPVIEFWERNVLSLSSGIDHPGSLKWDLALCLLLVWLVCFF 243

  Fly   385 C-----THNAKILR-RSIFVFGLVGLVLL---CTLTGWEVRNSFSRHYFPELWGFDSNLLAESNI 440
            |     ....|::. .:.|.|.:: ||||   .||.|  .......:.:|.:     :.|.:..:
  Rat   244 CIWKGVRSTGKVVYFTATFPFAML-LVLLVRGLTLPG--AGEGIKFYLYPNI-----SRLEDPQV 300

  Fly   441 WFNALMQVLFSVNCGFGALPMITGKFLYKGDAVRTSVVYLCFN---LLINAIAVTL---FMVQ-- 497
            |.:|..|:.||.....||:..:.....||.::.|..::..|.|   ..::..|:..   ||.|
  Rat   301 WIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQ 365

  Fly   498 ----FDLSSNG-------FQNMEELKPLTAIYDRVLNGSREGDSHLLQHLVPSLIYALIILSAMV 551
                .|::.:|       :.....:.||...:.                   .|.:.:::|..:.
  Rat   366 GVDIADVAESGPGLAFIAYPKAVTMMPLPTFWS-------------------ILFFIMLLLLGLD 411

  Fly   552 SITVAVYTS-TRLVPRRPNY------------VICLIGLVVAVISFAAPKFLIARVLDSRLV-GT 602
            |..|.|... |.||...|::            ::|.|..::.:.........:.::.|.... |.
  Rat   412 SQFVEVEGQITSLVDLYPSFLRKGYRREIFIAIVCSISYLLGLTMVTEGGMYVFQLFDYYAASGV 476

  Fly   603 MVVTALVFELIAITWIYGAKNIYTDLEFSIG-RPIFRVWM-WLW-VICPAILTGILVWWCADDDQ 664
            .::....||...|.||||..|:|..:|..|| ||  ..|| :.| ||.||:..|..::
  Rat   477 CLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRP--GPWMKYSWAVITPALCVGCFIF------- 532

  Fly   665 YDLLAEYL----------PRWA----------PILFVLAVIVIIAC 690
              .|.:|:          |.||          .::.:..||||:.|
  Rat   533 --SLVKYVPLTYNKVYRYPDWAIGLGWGLALSSMVCIPLVIVILLC 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	121/513 (24%)
Slc6a6	XP_008761345.1	SLC5-6-like_sbd	51..592	CDD:382020	131/566 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900