Protein Alignment blot and SLC6A16

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: XP_011525161.2
• Gene: SLC6A16 / 28968
• HGNCID: 13622
• Length: 781
• Species: Homo sapiens
• Alignment Length: 559
• Identity: 112/559 - (20%)
• Similarity: 199/559 - (35%)
• Gaps: 170/559 - (30%)

  Fly   242 LDRYGSAYLVPYVVLLFLVGLPMVLLEISVGQFLGQGAAHTWR-ASPIFKGACMISRFASWLSAI 305
            |:..|.::...|:.:|||||:|::.||::.||.:.||....|: .:|...|....|....::..:
Human   216 LNSGGCSFAAIYIFMLFLVGVPLLFLEMAAGQSMRQGGMGVWKIIAPWIGGVGYSSFMVCFILGL 280

  Fly   306 WVSLQAVLALAYIGMFASNDLPFRECAGPVKLRLSGYLLTGTSGQECLQLTFLTPFW-------- 362
            :.::.....:.|:.......:|:.:|  |:.:..||:      ..||.:.|....||
Human   281 YFNVVNSWIIFYMSQSFQFPVPWEKC--PLTMNSSGF------DPECERTTPSIYFWYQQALKAS 337

  Fly   363 ------RNPLYFGLLAAGLIGLWIVVMLCTHNAKILRRSIFVFGLVGLVLLCTLTGWEVRNSFSR 421
                  .:|:|         .|.:...||             :.|||..:   :.|.:.....|.
Human   338 DRIEDGGSPVY---------SLVLPFFLC-------------WCLVGAFM---INGLKSTGKISD 377

  Fly   422 HYFPELWGFDSNLLAESNIWFNALMQVLFSVNCGFGALPMITGKFLYKGDAVRTSVVYLCFNLLI 486
            .|             ..::|..|..|||.:...|.|::..:........:.:..:.:....|||
Human   378 VY-------------NMSVWSLAGGQVLSNTGIGLGSVASLASYMPQSNNCLSDAFLVSVINLL- 428

  Fly   487 NAIAVTLFMVQFDLSSNGF-----------QNMEELKPL--------------------TAIYDR 520
                ..|....|:....||           :|.|.|..|                    |:||:.
Human   429 ----TLLVFTSFNFCVLGFWATVITHRCCERNAEILLKLINLGKLPPDAKPPVNLLYNPTSIYNA 489

  Fly   521 VLNG------------------------SREGDS-------HLLQHLVPSLIYALII-------- 546
            .|:|                        :.||..       ..:..|.||:.::.|.
Human   490 WLSGLPQHIKSMVLREVTECNIETQFLKASEGPKFAFLSFVEAMSFLPPSVFWSFIFFLMLLAMG 554

  Fly   547 LSAMVSITVAVYTSTRLVPR-------RPNYVICLIG----LVVAVISFAAP--KFLIARVLDSR 598
            ||:.:.|...:.|     |.       |.:..:.::|    :.|..:.|..|  .:.| |:|...
Human   555 LSSAIGIMQGIIT-----PLQDTFSFFRKHTKLLIVGVFLLMFVCGLFFTRPSGSYFI-RLLSDY 613

  Fly   599 LVGTMVVTALVFELIAITWIYGAKNIYTDLEFSIGRPIFRVWMWLWV-ICPAIL----TGILVWW 658
            .:...::..:|||.:|::|.|||:....||...:|.||..::.|||. :||.:|    ..::|..
Human   614 WIVFPIIVVVVFETMAVSWAYGARRFLADLTILLGHPISPIFGWLWPHLCPVVLLIIFVTMMVHL 678

  Fly   659 CADDDQY---------DLLAEYLPRWAPILFVLAVIVII 688
            |.....|         ::|..| |.||.:|.:....::|
Human   679 CMKPITYMSWDSSTSKEVLRPY-PPWALLLMITLFAIVI 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	103/519 (20%)
SLC6A16	XP_011525161.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910