Protein Alignment blot and Slc6a18

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_001035782.1
• Gene: Slc6a18 / 22598
• MGIID: 1336892
• Length: 615
• Species: Mus musculus
• Alignment Length: 655
• Identity: 137/655 - (20%)
• Similarity: 239/655 - (36%)
• Gaps: 166/655 - (25%)

  Fly   197 ASNAKLLPAVEDESNKQTKCSVFRGLVLCLCLNLSYANVVRFPRELDRY-GSAYLVPYVVLLFLV 260
            ||....|..:|||..|..  :..:.|:.|:...:...|:.|||.....: |.|:|:||.:.|...
Mouse     4 ASGMDPLVDIEDERPKWD--NKLQYLLSCIGFAVGLGNIWRFPYLCQTHGGGAFLIPYFIALVFE 66

  Fly   261 GLPMVLLEISVGQFLGQGAAHTWRA-SPIFKGACMISRFASWLSAIWVSLQAVLALAYIGMFASN 324
            |:|:..:|:::||.|.:|:...|:. ||...|..:.....|:|    |||.....|.::..|..|
Mouse    67 GIPLFYIELAIGQRLRRGSIGVWKTISPYLGGVGLGCFSVSFL----VSLYYNTVLLWVLWFFLN 127

  Fly   325 D----LPFRECAGPVKLRLSGYLLTGTSGQECLQLTFLTPFW-RNPLYF-----------GLLAA 373
            .    ||:..|  |:.|..:|::      |||.....::.|| |..|..           ..|..
Mouse   128 SFQHPLPWSTC--PLDLNRTGFV------QECQSSGTVSYFWYRQTLNITSDISNTGTIQWKLFL 184

  Fly   374 GLIGLWIVVMLCT-----HNAKILR-RSIFVFGLVGLVLLCTLTGWEVRNSFSRHYFPELWGFDS 432
            .|:..|..|.||.     ...|::. .::|.:.::.:.|:..||...........:.|.:
Mouse   185 CLVACWSTVYLCVIRGIESTGKVIYFTALFPYLVLTIFLIRGLTLPGATEGLIYLFTPNM----- 244

  Fly   433 NLLAESNIWFNALMQVLFSVNCGFGALPMITGKFLYKGDAVRTSVVYLCFNLLINAIA-VTLFMV 496
            ..|....:|.:|..|:.||::..||...........:.:..:.:|:....|.:.:..| :.:|.|
Mouse   245 KTLQNPRVWLDAATQIFFSLSLAFGGHIAFASYNPPRNNCEKDAVIIALVNSMTSLYASIAIFSV 309

  Fly   497 ----------------------QFDLSS---------------NGFQ--NMEELKPLTAIYDRVL 522
                                  :|||..               |..|  .:.:|...|...:..|
Mouse   310 MGFKASNDYGRCLDRNILSLINEFDLPELSISRDEYPSVLMYLNATQTARVAQLPLKTCHLEDFL 374

  Fly   523 NGSREGD-------SHLLQHLVPSLIYALII--------LSAMVSITVAVYT---STRLVPRR-P 568
            :.|..|.       :..:.|:..:.:::::.        ||:|......|.|   ...::|:. |
Mouse   375 DKSASGPGLAFIVFTEAVLHMPGASVWSVLFFGMLFTLGLSSMFGNMEGVITPLLDMGILPKGIP 439

  Fly   569 NYVICLIGLVVAVISFAAPKFLIA------------RVLDSRLVGTMVVTALVFELIAITWIYGA 621
            ..|      :..||.||.  ||.|            .:.||......::.....|::.:..|||.
Mouse   440 KEV------MTGVICFAC--FLSAICFTLQSGGYWLEIFDSFAASLNLIIFAFMEVVGVIHIYGM 496

  Fly   622 KNIYTDLEFSIGRPIFRVWMWLW-VICPAILTGILVWWC-----------ADDDQYDLL----AE 670
            |....|:|:..||.....|...| |:.|.:|.||.:.:.           |.:.||:..    .:
Mouse   497 KRFCDDIEWMTGRRPGLYWQVTWRVVSPMLLFGIFLSYIVLLIQTPPSYKAWNPQYEHFPSREEK 561

  Fly   671 YLPRWAPILFVLAVIVIIACVQIFRQVEYNFFGMICEASKPAKEWGPADPLAR--HSWKQ-WRSV 732
            :.|.|          |.:.||.:      :|...:         |.|...||:  ..:|| |::.
Mouse   562 FYPGW----------VQVTCVLL------SFLPSL---------WVPGVALAQLLSQYKQRWKAT 601

  Fly   733 CQDTG 737
            ..::|
Mouse   602 HLESG 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	113/535 (21%)
Slc6a18	NP_001035782.1	SLC6sbd_B0AT3	16..591	CDD:212086	128/626 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000