Protein Alignment blot and dat-1

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_499043.1
• Gene: dat-1 / 176304
• WormBaseID: WBGene00000934
• Length: 615
• Species: Caenorhabditis elegans
• Alignment Length: 578
• Identity: 125/578 - (21%)
• Similarity: 214/578 - (37%)
• Gaps: 179/578 - (30%)

  Fly   234 NVVRFPRELDRY------GSAYLVPYVVLLFLVGLPMVLLEISVGQFLGQGAAHTW-RASPIFKG 291
            |:.|||     |      |..:|:||.:::.|.|:|:..:|:.:||:..:||..|| |..|:|||
 Worm    62 NIWRFP-----YLCFKNGGGVFLIPYSIMVLLTGVPLFYMELCLGQYYRKGAITTWGRICPLFKG 121

  Fly   292 A--CMISRFASWLSAIWVSL--QAVLA--LAYIGMFASNDLPFRECAGPVKLRLSGYLLTGTSGQ 350
            .  |:|      |:|.:|..  ..:||  |.|:....|.:||:..|.       :.|     :..
 Worm   122 IGYCVI------LTAFYVDFFYNVILAWGLHYLYTSFSFNLPWASCN-------NSY-----NSP 168

  Fly   351 ECLQLTFLTPFWRNP-----------------------LYFGLLAAGL----------------- 375
            .|.:     |.|...                       .|.|.|  ||
 Worm   169 ACYE-----PHWSEDGTAMCRSANQSVSAEKISAAEEYFYKGFL--GLHEANAPNSHVIRSVTDL 226

  Fly   376 --------IGLWIVVMLC---------THNAKILRRSIFVFGLVGLVLL--CTLTGWEVRNSFSR 421
                    :.|::|.::|         |....:...::|.:.::|::.:  .||.||:  |....
 Worm   227 GNVRWDIALSLFVVYLICYFSMWKGIHTSGKVVWFTALFPYVVLGILFIRGVTLPGWQ--NGIEY 289

  Fly   422 HYFPELWGFDSNLLAESNIWFNALMQVLFSVNCGFGALPMITGKFLYKGDAVRTSVVYLCFNLLI 486
            :..|..     .:|...::|.:|..||.||:..|||.| |....:   .|......|...|...|
 Worm   290 YLRPNF-----EMLKRPSVWQDAATQVFFSLGPGFGVL-MAYSSY---NDFHNNVYVDALFTSFI 345

  Fly   487 NAIAVTLFMVQFDL-SSNGFQNMEELKPLTAIYDRVLNGSREGDSHLLQHLVPSLIYALI----- 545
            |  ..|.|:..|.: |..|:.:.:..||:.|:       ::||         |.|::.:.
 Worm   346 N--CATSFLSGFVIFSVLGYMSCKSGKPIEAV-------AQEG---------PGLVFVVYPEALS 392

  Fly   546 ---------ILSAMVSITV----------AVYTSTR-----LVPRRPNYVICLIG--LVVAVISF 584
                     :|..::.:|:          |:.|...     |...|..:|.||..  :|:.:...
 Worm   393 TMPYAPFWSVLFFLMLMTLGLDSSFGGSEAIITGLSDEFPILKKNREVFVGCLFAFYMVIGIAMC 457

  Fly   585 AAPKFLIARVLDSRLVGTM--VVTALVFELIAITWIYGAKNIYTDLEFSIGRPIFRVWMWLW--- 644
            .....||...|  .:.||.  ::.|:..|.:.|.:|||.:....|::..:|......|.:.|
 Worm   458 TEGGILIMEWL--IIYGTTWGLLIAVFCEAMVIAYIYGLRQFVHDVKEMMGFRPGNYWKFCWSCA 520

  Fly   645 --VICPAILTGILVWWCA---DDDQYDLLAEYLPRWAPILFVLAVIVIIACVQIFRQV 697
              .|..:::|...:.:.|   .|..|...|..:    .|:|.|:....|..|.|::.|
 Worm   521 APFILLSMITSNFINYQALTYQDYTYPTAANVI----GIIFALSGASFIPLVGIYKFV 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	114/535 (21%)
dat-1	NP_499043.1	SLC6sbd_SERT-like_u1	40..591	CDD:271405	125/578 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810