Protein Alignment blot and Slc6a13

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_001366036.1
• Gene: Slc6a13 / 14412
• MGIID: 95629
• Length: 602
• Species: Mus musculus
• Alignment Length: 651
• Identity: 150/651 - (23%)
• Similarity: 239/651 - (36%)
• Gaps: 194/651 - (29%)

  Fly   196 TASNAKLLPA------VEDE--------SNKQTKCSVFRGLVLCLCLNLSYANVVRFPRELDRY- 245
            |.||.:..|.      ||::        :||........|.::.|      .||.|||     |
Mouse     8 TTSNGETKPVCPAMEKVEEDGTLEREHWNNKMEFVLSVAGEIIGL------GNVWRFP-----YL 61

  Fly   246 -----GSAYLVPYVVLLFLVGLPMVLLEISVGQFLGQGAAHTW-RASPIFKGACMISR-FASWLS 303
                 |.|:.:||::.||..|:|:..||.::||:..||....| |..|||:|....|: ..|.|:
Mouse    62 CYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTNQGGITAWRRICPIFEGIGYASQMIVSLLN 126

  Fly   304 AIWVSLQAVLALAYIGMFAS--NDLPFRECA------GPVKLRLSGYLLTGTSGQECLQLTFLTP 360
            ..::   .|||.|...:|:|  .|||:..|:      ..|:.:.:...:..||..   ..:.:..
Mouse   127 VYYI---VVLAWALFYLFSSFTTDLPWGSCSHEWNTENCVEFQKANDSMNVTSEN---ATSPVIE 185

  Fly   361 FWRN---PLYFGLLAAG---------LIGLWIVVMLCT-HNAKILRRSIF---VFGLVGLVLL-- 407
            ||..   .|..|:...|         |:..||:...|. ...|...:.::   .|..:.||:|
Mouse   186 FWERRVLKLSDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLI 250

  Fly   408 --CTLTGWEVRNSFSRHYFP---ELWGFDSNLLAESNIWFNALMQVLFSVNCGFGALPMITGKFL 467
              .||.|  .......:.:|   .||        :..:|.:|..|:.||.....|.|..:.....
Mouse   251 RGVTLPG--AAQGIQFYLYPNITRLW--------DPQVWMDAGTQIFFSFAICLGCLTALGSYNK 305

  Fly   468 YKGDAVRTSVVYLCFNLLINAIAVTLFMVQFDL-SSNGFQNMEELKPLTAI-----------YDR 520
            |..:..|..:. ||   ::|  :.|.||..|.: |..||.:.|:..|::.:           |.|
Mouse   306 YHNNCYRDCIA-LC---ILN--SSTSFMAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPR 364

  Fly   521 -------------------VLNGSREGDSHLLQHLVPSLIYALIILSAMVSITVAVYTSTRLVPR 566
                               ||.|.   ||..:  .|.||:.||:.:...|.             |
Mouse   365 AVVMLPFSPLWACCFFFMVVLLGL---DSQFV--CVESLVTALVDMYPRVF-------------R 411

  Fly   567 RPNYVICLIGLVVAVISFAAPKFLIA-------RVLDSRLV-GTMVVTALVFELIAITWIYGAKN 623
            :.|....|| |:|:||||.....::.       ::.|.... |..::...:||.:.:.|:|||..
Mouse   412 KKNRREVLI-LIVSVISFFIGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGAGR 475

  Fly   624 IYTDLEFSIGRPIFRVW-----MWLW---VICPAILTGILV--------------WWCADDDQYD 666
            .|.::|..||   ::.|     .||:   .:|.|.....|:              ||      .|
Mouse   476 FYDNIEDMIG---YKPWPLIKYCWLFFTPAVCLATFLFSLIKYTPLTYNKKYTYPWW------GD 531

  Fly   667 LLAEYLPRWAPILFVLAVIVIIACVQIFR------QVEYNFFGMICEASK-PAKE----WGPADP 720
            .|.     |   |..|:.::.|....|::      .:......::|.|.. |.|.    ..||.|
Mouse   532 ALG-----W---LLALSSMICIPAWSIYKLRTLKGPLRERLRQLVCPAEDLPQKNQPEPTAPATP 588

  Fly   721 L 721
            :
Mouse   589 M 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	127/539 (24%)
Slc6a13	NP_001366036.1	SLC5-6-like_sbd	32..575	CDD:382020	139/611 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810