DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment blot and AgaP_AGAP011279

DIOPT Version :9

Sequence 1:NP_524125.2 Gene:blot / 39939 FlyBaseID:FBgn0027660 Length:976 Species:Drosophila melanogaster
Sequence 2:XP_309367.2 Gene:AgaP_AGAP011279 / 1270651 VectorBaseID:AGAP011279 Length:681 Species:Anopheles gambiae


Alignment Length:757 Identity:158/757 - (20%)
Similarity:248/757 - (32%) Gaps:287/757 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 IGGAPTGGGNGNEQISVTLDRRQPQRMSWLNMRRAKANETDLPTVTPSPQTTRSCISTVSSVVDS 139
            :.|.|....||:|             |:.|| .||:.:.|...|:..|| ..||.|.        
Mosquito     5 VDGVPGPRNNGHE-------------MAPLN-TRARGDGTHGVTIMLSP-PDRSSIG-------- 46

  Fly   140 GGGRTTATSGRISSSGIVTLSDSNNTLSEIQGGYHDMDHDAVS--KNFSISASAHNITTASNAKL 202
                        |..|...|.|.            |.|..|.|  ..|.:|...:::        
Mosquito    47 ------------SREGAGALPDG------------DPDRAAWSGKMQFFLSIIGYSV-------- 79

  Fly   203 LPAVEDESNKQTKCSVFRGLVLCLCLNLSYANVVRFPRELDRY-GSAYLVPYVVLLFLVGLPMVL 266
                              ||          .|:.|||....:. |.|:|:|::::|.|.|:|:.|
Mosquito    80 ------------------GL----------GNIWRFPYLCQQNGGGAFLIPFMIMLILEGIPLFL 116

  Fly   267 LEISVGQFLGQGAAHTWRASPIFKG-----ACMISRFASWLSAIWVSLQAVLALAYIGMFASNDL 326
            :|:.:||.:..||...|.....:.|     :|:::.|.    ||:.::.......|........|
Mosquito   117 IELGMGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFV----AIYYNVIITWCFYYFFNSFRYPL 177

  Fly   327 PFRECAGPVKLRLSGYLLTGTSGQECLQLTFLTPFWRNPLYFGLLAA-------GLIGLWIVVML 384
            |:..|.          .|.||..:||.:.:....||    |...|.|       |....|||   
Mosquito   178 PWAVCP----------QLNGTDVEECERSSETAYFW----YRTTLDAAPSIDETGGFKWWIV--- 225

  Fly   385 CTHNAKILRRSIFVFGLVGLVLLCTLTGWEV---------RNSFSRHYFPELW------------ 428
                                  ||.:..|.|         ::|....||..|:            
Mosquito   226 ----------------------LCLMLSWTVVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRG 268

  Fly   429 ----GFDSNL----------LAESNIWFNALMQVLFSVNCGFGALPMITGKFLYKGDAVR-TSVV 478
                |..:.|          |.|..:|.:|..||.:|....||:|.........|.:.|| ..:|
Mosquito   269 ITLKGAGAGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLV 333

  Fly   479 YLCFNLLINAI-----AVTLFMV---------------------------QFDLSSNGFQN-MEE 510
            .:|     |||     :|.:|.:                           ..|:..:.::: |..
Mosquito   334 SVC-----NAITAIYASVVIFAILGYKATLGVDRCIQVNKHILVKHNLLPSMDVDQSEYEHAMAG 393

  Fly   511 L-KPLT--------AIYDRVLNGSREGD-------SHLLQHLVPSLIYALI-------------- 545
            | :.:|        ::.|: |:.:.||.       :..:..|..|..:|::              
Mosquito   394 LNETMTKDWEFEKCSLEDQ-LSSAAEGTGLAFIVFTEAIVELPGSPFWAVLFFTMLLSLGLGSQI 457

  Fly   546 -ILSAMVSITVAVYTSTRLVPRRP--NYVICLIGLVVAVISFAAPKFLIARVLDSRLVGT--MVV 605
             ||..|:.....:....|:  |:|  ..|:|.....|.:|..........::.|| ..||  :||
Mosquito   458 GILEGMLCTIFDIDIFKRI--RKPYVTGVVCAFCFSVGLIFTTGAGEYWLKMFDS-FAGTIGLVV 519

  Fly   606 TALVFELIAITWIYGAKNIYTDLEFSIG-RPIFRVWMWLW-VICPAILTGILV------------ 656
            .||: |:||:.:|||.:....|:....| ||.. .|...| .|.|||:..||:            
Mosquito   520 VALM-EMIAVIYIYGHEKFTEDIYQMTGIRPGL-YWQMTWRYIGPAIMGCILLSSILSMLLRNPT 582

  Fly   657 --WWCAD-----DDQYDLLAEYLPRWAPILFVLAVIVIIACV 691
              .|..|     :..|       |.|   :..:|:.:|||.|
Mosquito   583 YGAWNGDLGIVENKSY-------PNW---VMGIALAMIIAGV 614

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
blotNP_524125.2 SLC5-6-like_sbd 219..659 CDD:271356 121/572 (21%)
AgaP_AGAP011279XP_309367.2 SLC6sbd-B0AT-like 61..624 CDD:271364 135/654 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0733
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.