Protein Alignment blot and SLC6A14

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_009162.1
• Gene: SLC6A14 / 11254
• HGNCID: 11047
• Length: 642
• Species: Homo sapiens
• Alignment Length: 660
• Identity: 144/660 - (21%)
• Similarity: 249/660 - (37%)
• Gaps: 170/660 - (25%)

  Fly   187 ISASAHNITTASNAKLLPAVEDESNKQTKCSVFRGLVLCLCLNLSYA----NVVRFP-RELDRYG 246
            :|||:.|.....|        ||:..:...|.....:|.:   :.||    ||.||| ......|
Human    18 VSASSENFHVGEN--------DENQDRGNWSKKSDYLLSM---IGYAVGLGNVWRFPYLTYSNGG 71

  Fly   247 SAYLVPYVVLLFLVGLPMVLLEISVGQFLGQGAAHTWRASPIFKGA----CMISRFASWLSAIWV 307
            .|:|:||.::|.|.|||:..||.|:|||...|....||..|:|:|.    .:||.|      :.:
Human    72 GAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVWRILPLFQGVGITMVLISIF------VTI 130

  Fly   308 SLQAVLALAYIGMFAS--NDLPFRECA---------GPVKLRLSGYLLTGTSG-QECLQLTFLTP 360
            ....::|.:...||||  ::||::.|:         .|:....:  :.|...| ||.:|:.
Human   131 YYNVIIAYSLYYMFASFQSELPWKNCSSWSDKNCSRSPIVTHCN--VSTVNKGIQEIIQMN---- 189

  Fly   361 FWRNPLYFGLLAAGLIGLWIVV--MLCTHNAKI----------------LRRS-------IFVFG 400
                            ..|:.:  ..|.:.::|                |:||       :.|:.
Human   190 ----------------KSWVDINNFTCINGSEIYQPGQLPSEQYWNKVALQRSSGMNETGVIVWY 238

  Fly   401 LVGLVLLCTLTGW---------EVRNSFSRHYFPELW--------------------------GF 430
            |.    ||.|..|         .:::|....||..|:                          |.
Human   239 LA----LCLLLAWLIVGAALFKGIKSSGKVVYFTALFPYVVLLILLVRGATLEGASKGISYYIGA 299

  Fly   431 DSNL--LAESNIWFNALMQVLFSVNCGFGALPMITGKFLYKGDAVRTSVVYLCFNLLINAIA-VT 492
            .||.  |.|:.:|.:|..|:.:|::..:|.|..::....:|.:....::|....|.|.:..| ..
Human   300 QSNFTKLKEAEVWKDAATQIFYSLSVAWGGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFA 364

  Fly   493 LFMVQFDLSSNGFQNMEELKPLTAIYDRVLNGSREGDSHLLQHLVPSLIYALIIL-----SAMVS 552
            :|.:...::.  ....|..:.:.:.:|.......|..:.|......|:::..::|     |...|
Human   365 IFSILGHMAH--ISGKEVSQVVKSGFDLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFAS 427

  Fly   553 ITVAVYTSTRLVPRRPNYV-------ICLIGLVVAVISFAAPKFLIARVLDSRLVGTMVVTALVF 610
            |.....|...|.|:....:       .||:..::.::...........::|....|..::.|.:.
Human   428 IETITTTIQDLFPKVMKKMRVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAIL 492

  Fly   611 ELIAITWIYGAKNIYTDLEFSIGRPIFRVWMW---LW-VICPAILTGILVWWCADDDQYDLLAEY 671
            ||:.|.||||......|.|..||...:..|:|   .| ||.|.:|..|.:|        .|:..:
Human   493 ELVGIIWIYGGNRFIEDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIW--------SLVQFH 549

  Fly   672 LPR--------------WAPILFVLAVIVIIACVQIFRQVEYNFFGMICEASKPAKEWGPADPLA 722
            .|.              |..|:|.:..|.|:|.::|. |.:.|.|..:....:||..|||.  |.
Human   550 RPNYGAIPYPDWGVALGWCMIVFCIIWIPIMAIIKII-QAKGNIFQRLISCCRPASNWGPY--LE 611

  Fly   723 RHSWKQWRSV 732
            :|..::::.:
Human   612 QHRGERYKDM 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	117/539 (22%)
SLC6A14	NP_009162.1	SLC6sbd_ATB0	36..641	CDD:271391	137/634 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	622..642		144/660 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810