Protein Alignment blot and Slc6a15

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_001239259.1
• Gene: Slc6a15 / 103098
• MGIID: 2143484
• Length: 729
• Species: Mus musculus
• Alignment Length: 652
• Identity: 128/652 - (19%)
• Similarity: 241/652 - (36%)
• Gaps: 157/652 - (24%)

  Fly   175 DMDHDAVSKNFSISASAHNITTAS-NAKLLPAVEDESNKQTK------------CSVFRGLVLCL 226
            |:|.|.:.....:.::..::...| .::|:..|::|.:...:            .|..:.::..:
Mouse    11 DLDDDVIESVKDLLSNEDSVEEVSKKSELIVDVQEEKDTDAEDGSEADDERPAWNSKLQYILAQV 75

  Fly   227 CLNLSYANVVRFPRELDRY-GSAYLVPYVVLLFLVGLPMVLLEISVGQFLGQGAAHTWR-ASPIF 289
            ..::...||.|||....:. |.|||:||::||.::|:|:..||:||||.:.:|:...|. .||..
Mouse    76 GFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLLVIGIPLFFLELSVGQRIRRGSIGVWNYISPKL 140

  Fly   290 KGACMISRFASWLSAIWVSLQAVLALAYIGMFASNDLPFRECAGP-VKLRLSGYLLTGTSGQECL 353
            .|....|....:..|::.::.....|.|........||:.:|  | ||.....|:     ..||.
Mouse   141 GGIGFASCVVCYFVALYYNVIIGWTLFYFSQSFQQPLPWDQC--PLVKNASHTYV-----EPECE 198

  Fly   354 QLTFLTPFW-RNPLYF--------GL---LAAGLIGLWIVVMLC-----THNAKILR-RSIFVFG 400
            |.:..|.:| |..|..        ||   :...|:..|::|.|.     ..:.||:. .|:|.:
Mouse   199 QSSATTYYWYREALDITSSISDSGGLNWKMTVCLLVAWVMVCLAMIKGIQSSGKIMYFSSLFPY- 262

  Fly   401 LVGLVLLCTLTGWEVRNSF---SRHYF-PELWGFDSNLLAESNIWFNALMQVLFSVNCGFGALPM 461
               :||:|.|....:.|..   .||.| |:|     .::.|..:|..|..||.|::..|||.:..
Mouse   263 ---VVLICFLIRSLLLNGSIDGIRHMFTPKL-----EMMLEPKVWREAATQVFFALGLGFGGVIA 319

  Fly   462 ITGKFLYKG-------DAVRTSVVYLCFNLLINAIAVTLFMVQFDLSSNGF------QNME---- 509
            .:.   |..       |||..|.:    |...:.:|..:........:|..      ||.|
Mouse   320 FSS---YNKRDNNCHFDAVLVSFI----NFFTSVLATLVVFAVLGFKANIVNEKCISQNSEMILK 377

  Fly   510 ----------------ELKPLTA-----IYDRV---------------------LNGSREGD--- 529
                            .|..:|.     :||.:                     ||.:.:|.
Mouse   378 LLKMGNISWDVIPHHINLSAVTVEDYRLVYDIIQKVKEEEFAVLHLNACQIEDELNKAVQGTGLA 442

  Fly   530 ----SHLLQHLVPSLIYALIILSAMVS------------ITVAVYTSTRLVPRRPNYVICLIGLV 578
                :..:.|...|..::::....:::            |...:..:.::.......:.||:...
Mouse   443 FIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMFGTIEGIITPIVDTFKVRKEILTVICCLLAFC 507

  Fly   579 VAVISFAAPKFLIARVLDSRLVGTMVVTALVFELIAITWIYGAKNIYTDLEFSIGRPIFRVWMWL 643
            :.:|...........:.|.......::..::.|.||::::||......||...:|....:.:.::
Mouse   508 IGLIFVQRSGNYFVTMFDDYSATLPLLIVVILENIAVSFVYGIDKFIEDLTDMLGFAPSKYYYYM 572

  Fly   644 W-VICPAILTGILV--------------WWCADDDQYDLLAEYLPRWAPIL-FVLAVIVIIACVQ 692
            | .|.|.:|..:|:              .|..:....:.|:  .|.|..:: |.|.|:.|:....
Mouse   573 WKYISPLMLLTLLIASIVNMGLSPPGYNAWIKEKASEEFLS--YPMWGMVVCFSLMVLAILPVPV 635

  Fly   693 IF 694
            :|
Mouse   636 VF 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	111/557 (20%)
Slc6a15	NP_001239259.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..61		2/18 (11%)
		SLC6sbd_SBAT1	61..640	CDD:212091	121/602 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000