Protein Alignment blot and slc6a6

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: XP_017949178.2
• Gene: slc6a6 / 100494063
• XenbaseID: XB-GENE-991256
• Length: 616
• Species: Xenopus tropicalis
• Alignment Length: 593
• Identity: 134/593 - (22%)
• Similarity: 219/593 - (36%)
• Gaps: 170/593 - (28%)

  Fly   230 LSYANVVRFPRELDRY------GSAYLVPYVVLLFLVGLPMVLLEISVGQFLGQGAAHTW-RASP 287
            :...||.|||     |      |.|:|:||.:.||..|||:..||:.:|||..:|....| :..|
 Frog    59 IGLGNVWRFP-----YLCYKNGGGAFLIPYFIFLFGGGLPVFFLEVVLGQFTSEGGITCWEKICP 118

  Fly   288 IFKGACMISRFASWLSAIWVSLQ-----AVLALAYIGMFAS--NDLPFRECAGPVKLRLSGYLLT 345
            :|.|       ..:.|.:.|||.     .:||.....:|.|  ..||:..|..|
 Frog   119 VFTG-------IGYASIVIVSLLNVYYIVILAWGVYYLFQSFQGQLPWALCHQP----------- 165

  Fly   346 GTSGQECLQLTF------------------LTPFWRN---PLYFGL---------LAAGLIGLWI 380
             .:.:.|::.||                  :|.||.:   .|..|:         ||..|:..|:
 Frog   166 -WNTESCVEDTFRKNWTMWMSMNSTNFTSPVTEFWEHKVLSLSKGIDDVGVLKWDLALCLLLTWV 229

  Fly   381 VVMLC-----THNAKILRRSI---FVFGLVGLVLLCTLTGWEVRNSFSRHYFPELWGFDSNLLAE 437
            :...|     ....|::..:.   |:..||.|:...||.|  .......:.:|     |...||:
 Frog   230 ICFFCIWKGVRSTGKVVYFTATFPFIMLLVLLIRGVTLPG--AAEGIKFYLYP-----DITRLAD 287

  Fly   438 SNIWFNALMQVLFSVNCGFGALPMITGKFLYKGDAVRTSVVYLCFN---LLINAIA---VTLFMV 496
            ..:|.:|..|:.||.....||:..:.....||.:..|..::..|.|   ..::..|   |..||.
 Frog   288 PQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNCYRDCMLLGCLNSGTSFVSGFAIFSVLGFMA 352

  Fly   497 Q------FDLSSNG-------FQNMEELKPLTAIYDRVLNGSREGDSHLLQHLVPSLIYALIILS 548
            |      .|::.:|       :.....:.||.:.:                   ..|.:.:::|.
 Frog   353 QEQGVDIADVAESGPGLAFIAYPKAVSMMPLPSFW-------------------AILFFIMLLLL 398

  Fly   549 AMVSITVAVYTS-TRLVPRRPNY------------VICLIGLVVAVISFAAPKFLIARVLDSRLV 600
            .:.|..|.|... |.||...|::            |:|.:..::.:.........:.::.|....
 Frog   399 GLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAVVCFLSYLLGLTMVTEGGMYVFQLFDYYAA 463

  Fly   601 -GTMVVTALVFELIAITWIYGAKNIYTDLEFSIG-RPIFRVWM-WLW-VICPAILTGILVWWCAD 661
             |..::....||.:|:.|:|||...|.::|..|| :|  ..|| |.| ||.|.:.....::
 Frog   464 SGVCLLWVAFFECVAVAWVYGADKFYDNIEDMIGYKP--GPWMKWSWTVITPLLCVACFIF---- 522

  Fly   662 DDQYDLLAEY----------LPRWAPIL-FVLAV--IVIIACVQIFRQVEYNFFGMICE------ 707
                 .||:|          .|.||..| :|||:  ::.|..|.:|..|..:  |.:.|
 Frog   523 -----SLAKYTPLTYNKYYVYPDWAIGLGWVLALSSMICIPLVVVFHIVRSD--GSLIERIKAVT 580

  Fly   708 ASKPAKEW 715
            |.:....|
 Frog   581 APREVNRW 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	116/516 (22%)
slc6a6	XP_017949178.2	SLC6sbd_TauT	41..582	CDD:271398	132/585 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910