Protein Alignment blot and slc6a8

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: XP_002935539.1
• Gene: slc6a8 / 100489909
• XenbaseID: XB-GENE-986840
• Length: 644
• Species: Xenopus tropicalis
• Alignment Length: 532
• Identity: 115/532 - (21%)
• Similarity: 193/532 - (36%)
• Gaps: 128/532 - (24%)

  Fly   222 LVLCLCLNLSYANVVRFPRELDRY------GSAYLVPYVVLLFLVGLPMVLLEISVGQFLGQGAA 280
            ::.|:...:...||.|||     |      |..:|:||:::..|.|:|:..|||::|||:..|:.
 Frog    68 IMSCVGFAVGLGNVWRFP-----YLCYKNGGGVFLIPYILIAILGGIPIFFLEIALGQFMKAGSI 127

  Fly   281 HTWRASPIFKGACMISRFASWLSAIWVSLQAVLALA----YIGMFASNDLPFRECAGP------V 335
            ..|..:|:|:|.    .|||.:...:.:...:|.|.    |:....|..||:..|...      |
 Frog   128 AVWNIAPLFQGI----GFASVVIVFFCNTYYILILTWGVYYLVKSFSAVLPWSHCNNTWNSPDCV 188

  Fly   336 KLRLSGYLLTGTSGQECLQLTF---------LTPFWRNP---LYFGL---------LAAGLIGLW 379
            .:........||:......||.         :|.||...   |..||         |...|||.|
 Frog   189 DIFRQEDCTNGTANSTFGNLTCNELADKVSPITEFWEKKVLRLSSGLDDIGSINWELLLCLIGCW 253

  Fly   380 IVVMLCT-HNAKILRRSIFVFGLVGLVLLCTLTGWEVRNSFSR-------HYFPELWGFDSNLLA 436
            ::|..|. ...|...:.::.......|:|..|.   ||.:...       :|....|    :.|.
 Frog   254 LLVYFCVWKGVKSTGKIVYFTATFPYVVLLILL---VRGAMLPGATEGIIYYLKPDW----SKLG 311

  Fly   437 ESNIWFNALMQVLFSVNCGFGALPMITGKFLYKGDAVRTSVVYLCFNLLINAIAVTLFMVQFDL- 500
            .:.:|.:|..|:.||...|.|||..:.....:..|..:.:.:....|      :.|.|...|.:
 Frog   312 TAQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNDCYKDAFILAVIN------SGTSFFAGFVVF 370

  Fly   501 SSNGFQNMEELKPLTAI-----------YDRVLNGSREGDSHLLQHLVP---SLIYALIIL---- 547
            |..||...|:...::.:           |.|.::         |..:.|   :|.:.:::|
 Frog   371 SILGFMANEQGVDISKVAESGPGLAFIAYPRAVS---------LMPVAPLWSALFFFMLLLLGLD 426

  Fly   548 SAMVSITVAVYTSTRLVPRRPNY---------VICLIGLVVAVISFAAPKFLIARVLDSRLVGTM 603
            |..|.:...:.....|:|.|..:         :.|.|..::.:.........:.::.|......|
 Frog   427 SQFVGVEGLITAILDLLPARYYFRFQREIAVAICCAIMFLIDLSMLTEGGMYVFQLFDYYSASGM 491

  Fly   604 VVTALVF-ELIAITWIYGAKNIYTDLEFSIG-RPIFRVWM-WLW-----VICPAILTGILV---- 656
            .:....| :.:.:.|:|||.....|:...|| ||.  .|| |.|     .:|.||....|:
 Frog   492 TLLWQTFWQCVVVAWVYGADRFMDDIARMIGYRPF--PWMKWCWSFVTPFVCMAIFLFNLINYKP 554

  Fly   657 ----------WW 658
                      ||
 Frog   555 LTYNNSYTYPWW 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	115/532 (22%)
slc6a8	XP_002935539.1	SLC5-6-like_sbd	58..644	CDD:382020	115/532 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810