DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment blot and slc6a19

DIOPT Version :9

Sequence 1:	NP_524125.2	Gene:	blot / 39939	FlyBaseID:	FBgn0027660	Length:	976	Species:	Drosophila melanogaster
Sequence 2:	NP_001120585.1	Gene:	slc6a19 / 100145739	XenbaseID:	XB-GENE-5870378	Length:	636	Species:	Xenopus tropicalis

Alignment Length:	600	Identity:	128/600 - (21%)
Similarity:	229/600 - (38%)	Gaps:	130/600 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 LVLCLCLNLSYANVVRFPRELDRY-GSAYLVPYVVLLFLVGLPMVLLEISVGQFLGQGAAHTWRA 285
            ::.|:...:...||.|||.....: |.|:::|:::||...|:|::.||.::||.|.:|:...|..
Frog    42 MLTCIGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVFEGIPLLHLEFAIGQRLRKGSVGVWST 106

  Fly   286 -SPIFKGACMISRFASWLSAIWVSLQAVLALAYIGMFASNDLPFRECAGPVKLRLSGYLLTGTSG 349
             .|..||..:.|...|:|..::.:......:.|........||:..|  |:....:.|:
Frog   107 IHPTLKGVGIASMLVSFLVGLYYNTIIAWVMWYFFNSFQEPLPWSVC--PLNANRTEYV------ 163

  Fly   350 QECLQLTFLTPFW-RNPLYFGL-----------LAAGLIGLWIVVMLCT-HNAKILRRSIFVFGL 401
            .||.:.:.:..|| |..|....           |...|...|.|:.:|| ...:...::::|...
Frog   164 SECARSSSVDYFWYRETLNTSTKIDDSGNLQWWLVLCLACAWGVLYVCTIRGIETTGKAVYVTST 228

  Fly   402 VGLVLLC--TLTGWEVRNSFSRHYFPELWGFDSNLLAESNIWFNALMQVLFSVNCGFGALPMITG 464
            :..::|.  .:.|..::.|.:...:  |:..|.:.||....|.:|..||.:|.:..||.|...:.
Frog   229 LPYLVLTIFLIRGLTLKGSVNGIIY--LFTPDISELANPVTWLDAGAQVFYSFSLAFGGLISFSS 291

  Fly   465 KFLYKGDAVRTSVVYLCFNLLINAIAVTLF--------MVQFD-------LSSNGFQNMEELKPL 514
            ......:..|.:|:....|...:..:.|:.        ..::|       ||.....::.|....
Frog   292 YNSVHNNCERDAVIISVINGFTSVYSATVIYSIIGFRATARYDDCVDSNILSLTNAFDLPEGNIT 356

  Fly   515 TAIYDRVLNGSREGDSHLLQHL-------------------------------VP-----SLIYA 543
            ...||.:||...:.:|.|:..|                               :|     |:::.
Frog   357 QDNYDSMLNHLNQSNSDLVSTLKLETCDLDQILSDGVEGTGLAFIVFTEAITKMPISPLWSVLFF 421

  Fly   544 LII----LSAMVSITVAVYT---STRLVPRR-PNYVICLIGLVVAVISFAAPKFLIAR--VLDS- 597
            :::    ||:|......|..   ..:::|:. |...:  .||:.||      .||||.  ||:|
Frog   422 IMLFCLGLSSMFGNMEGVLVPLLDLKIIPKSFPKEAV--TGLICAV------SFLIALIFVLESG 478

  Fly   598 --------RLVGTMVVTALVF-ELIAITWIYGAKNIYTDLEFSIGRPIFRVWMWLW-VICPAILT 652
                    ...|::.:..:.| |:.::.:|||......|::|.||......|...| ||.|.::.
Frog   479 NYWLALFDGFAGSIPLLIIAFCEMFSVVYIYGIDRFNEDIKFMIGHKPNIFWQATWRVISPLLML 543

  Fly   653 GILVW--------------WCADDDQY-DLLAEYLPRWAPILFVLAVIVIIACVQ---IFRQVEY 699
            .|.::              |..|.:|: ....|..|.|     |.|:|||:|.|.   |.....|
Frog   544 VIFLFYFVVKVTQKLEYITWDPDYEQFPKSKPESYPAW-----VYAIIVILAGVPSLVIPVYAIY 603

  Fly   700 NFFGMICEASKPAKE 714
            .|....|...:..:|
Frog   604 KFIRNCCTKDEDQRE 618

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	110/539 (20%)
slc6a19	NP_001120585.1	SLC6sbd_B0AT1	32..612	CDD:212085	127/592 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100