Protein Alignment blot and slc6a18

DIOPT Version :9

• Sequence 1: NP_524125.2
• Gene: blot / 39939
• FlyBaseID: FBgn0027660
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_001108369.1
• Gene: slc6a18 / 100141332
• ZFINID: ZDB-GENE-080219-9
• Length: 618
• Species: Danio rerio
• Alignment Length: 629
• Identity: 141/629 - (22%)
• Similarity: 238/629 - (37%)
• Gaps: 145/629 - (23%)

  Fly   222 LVLCLCLNLSYANVVRFPRELDRY-GSAYLVPYVVLLFLVGLPMVLLEISVGQFLGQGAAHTWRA 285
            |:.|:...:...|:.|||.....| |.|:|:||::.|...|||::.||:::||.|.:|:...|.:
Zfish    23 LLTCVGFAVGLGNIWRFPYLCQIYGGGAFLIPYLIALVFEGLPLLYLELAIGQSLRKGSIGVWHS 87

  Fly   286 -SPIFKGACMISRFASWLSAIWVSLQAVLALAYIGMFASNDLPFRECAGPVKLRLSGYLLTGTSG 349
             ||:..|..:.|...|:|..::.:......|.|......:.||:.:|  |:...|.||:
Zfish    88 ISPLLGGVGVASMVVSFLVGLFYNTILAWVLWYFFHSFEDPLPWSQC--PINDNLEGYV------ 144

  Fly   350 QECLQLTFLTPFW-RNPLYFG-----------LLAAGLIGLWIVVMLC-THNAKILRRSIFVFG- 400
            :||:..|.:..:| |..|...           .|...|...|.:|.:| ....:.:.::::|..
Zfish   145 EECVSSTPVNYYWYRQTLNISPDIEQSGSLQWTLVLCLATAWSIVYICFIRGIETIGKAVYVTAT 209

  Fly   401 ------LVGLVLLCTLTGWEVRNSFSRHYFPELWGFDSNLLAESNIWFNALMQVLFSVNCGFGAL 459
                  .:.||...||.|   .....::.|...|    .||....:|.:|..|:.||::..||.|
Zfish   210 FPYLVLTIFLVRALTLPG---ATDGLQYLFTPDW----TLLTNPQVWLDAATQIFFSLSLAFGGL 267

  Fly   460 PMITGKFLYKGDAVRTSVVYLCFNLLINAIAVTLF-------MVQFDLSSNGFQNM--EELKPLT 515
            ...:.....|.|..|.::    |..:||: |.:|:       ::.|..:|| |.:.  ..:..||
Zfish   268 IAFSSYNPKKNDCERDAL----FVGIINS-ATSLYASIPIFAILGFKATSN-FNSCVNSNILDLT 326

  Fly   516 AIYD---------------RVLNGSREG--DSHLLQHLV-------------------------- 537
            ..:|               |.||.|...  .|..|:|.|
Zfish   327 NAFDIGDRNITIENYDSWLRDLNASDPDRVSSLNLKHCVLKNFLDQSASGTGLAFIVFTEAVIEM 391

  Fly   538 -PSLIYALII--------LSAMVSITVAVYT---STRLVPR-RPNYV----ICLIGLVVAVISFA 585
             .|.::|::.        ||:|......|.|   ...:||| .|..:    ||::..:||:|...
Zfish   392 PGSQVWAVLFFVMLFSLGLSSMFGNLEGVLTPLLDLHMVPRWMPKEIFTGLICVVNFLVALIFTL 456

  Fly   586 APKFLIARVLDSRLVGTMVVTALVFELIAITWIYGAKNIYTDLEFSIGRPIFRVWMWLWV-ICPA 649
            ........:.:|.:....::....||:||:...||.|....|:|...||.....|...|: |.|.
Zfish   457 GSGNYWLEIFNSYVGSVPLLVIAFFEIIAVVCFYGIKRFSDDIEQMTGRRPNLFWRCCWMGISPV 521

  Fly   650 ILTGILVWWCADDDQ----YDLLAEYLPRWAP-------------ILFVLAVIVIIACVQIFRQV 697
            :|..:||.:.....|    |       |.|.|             ..:|.::.|:::.|.:....
Zfish   522 MLLVVLVAYVVVQVQKHPTY-------PAWNPQYENFPETEEKPYSTWVFSICVLLSSVPVISIP 579

  Fly   698 EYNFFGMICEASKPAKEWGPADPLARHSWKQWRSVCQDTGRRDF 741
            ....:.:|...:.|..  |..:|....|:      ..||..:.|
Zfish   580 IVALYRLIRRHTHPHS--GYPNPYTNQSY------TDDTHTQSF 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
blot	NP_524125.2	SLC5-6-like_sbd	219..659	CDD:271356	125/528 (24%)
slc6a18	NP_001108369.1	SLC5-6-like_sbd	12..587	CDD:294310	133/591 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010