DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Cad74A and Cdh9

DIOPT Version :10

Sequence 1:NP_648973.1 Gene:Cad74A / 39936 FlyBaseID:FBgn0036715 Length:1820 Species:Drosophila melanogaster
Sequence 2:XP_011243639.1 Gene:Cdh9 / 12565 MGIID:107433 Length:867 Species:Mus musculus


Alignment Length:576 Identity:156/576 - (27%)
Similarity:259/576 - (44%) Gaps:103/576 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly  1088 DERLGYHKIIYSLQGEHA-MLFDINNTTGEIIVASGQTIDRERTPRIQLQIKAED-SPGRPTDAK 1150
            |:..|...:.|.|.|:.| .||.|:..||:|..|  :.:|||......|:.||.| ..||..:.:
Mouse   158 DQDKGDGNLKYILTGDGAGNLFVIDENTGDIHAA--KRLDREEKSLYILRAKAIDRKTGRQVEPE 220

  Fly  1151 QSVVELQIEVLDVNDNAPEFTQKKYSTVIPENAQIDSFVLQLEAVDADE---GLGGEVRYELVNE 1212
            .   |..|::.|:|||.|:||:..|:..:||.:.:.:.|:|:.|.|||:   |...:|.|.::  
Mouse   221 S---EFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSIL-- 280

  Fly  1213 GEANGLFKIDTKSGLISTRRNLTGKGRAHPYVLIVRAQDNGNQMPKQPTLSTDTDVRIYIGDVSA 1277
             :....|.:|.:||:|.|......:.....|.::::|:|.|.||   ..||..|.|.|.:.||  
Mouse   281 -QGQPYFSVDPESGIIKTALPDMSRENKEQYQVVIQAKDMGGQM---GGLSGTTTVNITLTDV-- 339

  Fly  1278 NDGVPYFLSPRVGQMANVTENAVTGAPVFQVIASDPD---------DESTPSGTITYRILPDTPD 1333
            |:..|.|  |:.....|..|:|..|..:.::.|:|||         ..:...|:..:.::.|.  
Mouse   340 NNNPPRF--PQSTYQFNSLESAPLGTHLGRIKANDPDMGENAELEYSIAEGEGSDMFDVITDK-- 400

  Fly  1334 AEAFVIDAHSGLITTRQSMDRETKDMYRILLEVSDN---------GQPKQSATRILQIAILDVDD 1389
                  |...|:||.:|::|.|.|.:|.:.::.|:.         |..|.||  :::|::.|||:
Mouse   401 ------DTQEGIITVKQNLDFEKKMLYTLRVDASNTHPDPRFLHLGPFKDSA--MVKISVEDVDE 457

  Fly  1390 HEPRFAREADAGPLS--MSVREEEPAGTIVGNFSALDEDLGENAAIDYVIIDGNN--EQLFTIER 1450
             .|.|::      ||  |.|.|:...|:|:|..:|.|.| ..|..|.| .:|.:.  :::|:|..
Mouse   458 -PPVFSK------LSYLMEVDEDVKEGSIIGQVTAYDPD-AMNNIIKY-SVDRHTDMDRVFSIHS 513

  Fly  1451 NNESLAILKTKKPIDREQVESFTLTIKCLKLGEPGYKFIGDPYDRQDLSHLRINVRVLDIDDNLP 1515
            .|.|:.   |.||:|||......:||...::..|           :..|.:.:.:|:|||:|:.|
Mouse   514 ENGSIF---TLKPLDRESSPWHNITITATEINNP-----------KQSSQIPVFIRILDINDHAP 564

  Fly  1516 KFEQPDPTVGIRINVPIDTVVTTLKASDADAEAPPVGLSIENVTF--VPQFYKRSRSLAVGNLHN 1578
            :|.....|. :..|.....::.|:...|.|  .||.|   ....|  ||:|........|.|..|
Mouse   565 EFATYYETF-VCENAKSGQLIQTISVMDKD--DPPRG---HKFFFEPVPEFPLNPNFTIVDNKDN 623

  Fly  1579 LFTLNNRTGELRTGGSFADYVDGY-------FLMRVMANNSVQPKRQAHSNLKVFV 1627
            ...:..|.             |||       :|:.|:..::..|.:.:...|.:.|
Mouse   624 TAGIVTRK-------------DGYSRNKMNTYLLPVLIFDNDYPIQSSTGTLTIRV 666

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cad74ANP_648973.1 Cadherin_repeat 33..124 CDD:206637
Cadherin_repeat 132..240 CDD:206637
Cadherin_repeat 249..361 CDD:206637
Cadherin_repeat 487..581 CDD:206637
Cadherin_repeat 589..686 CDD:206637
Cadherin_repeat 713..810 CDD:206637
Cadherin_repeat 819..936 CDD:206637
Cadherin_repeat 953..1049 CDD:206637
Cadherin_repeat 1057..1166 CDD:206637 26/79 (33%)
Cadherin_repeat 1175..1279 CDD:206637 31/106 (29%)
Cadherin_repeat 1293..1390 CDD:206637 28/114 (25%)
Cadherin_repeat 1402..1513 CDD:206637 33/114 (29%)
Cadherin_repeat 1523..1628 CDD:206637 24/114 (21%)
Cdh9XP_011243639.1 Cadherin_repeat 150..233 CDD:206637 26/79 (33%)
Cadherin_repeat 242..342 CDD:206637 32/107 (30%)
Cadherin_repeat 350..457 CDD:206637 27/116 (23%)
Cadherin_repeat 465..562 CDD:206637 32/112 (29%)
Cadherin_repeat 570..667 CDD:206637 24/116 (21%)
CADH_Y-type_LIR 801..860 CDD:460041
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.