Protein Alignment Cad74A and cdh10b

DIOPT Version :10

• Sequence 1: NP_648973.1
• Gene: Cad74A / 39936
• FlyBaseID: FBgn0036715
• Length: 1820
• Species: Drosophila melanogaster
• Sequence 2: XP_073774932.1
• Gene: cdh10b / 100534755
• ZFINID: ZDB-GENE-130530-1019
• Length: 776
• Species: Danio rerio
• Alignment Length: 750
• Identity: 189/750 - (25%)
• Similarity: 307/750 - (40%)
• Gaps: 132/750 - (17%)

  Fly   936 NPVFKNTGWTSSRPVIDVKIKEEMPID--SALFILQAEDPVTRQPITSFELIEPKQVDYFQVAER 998
            |..|....||.:......|:..:|..:  :..::|..|...|                .|::.|.
Zfish    48 NSFFLLEEWTGTGKQYVGKLHSDMDTEDGNVKYVLTGEGAGT----------------VFEIDEN 96

  Fly   999 TGEVILKKRLDYEALGDTGPEFELQVRA----NSADRQRSTVSRVNITVENVNDNSPRFERNSYQ 1059
            :|::...:|||.|...    .:.|..:|    :..|.:|:  |...|.:.::|||.|:|.:::|.
Zfish    97 SGDIHATRRLDREEKA----SYTLSAKAVNKTSGQDLERA--SEFIIKIHDINDNEPKFAKDTYV 155

  Fly  1060 ATIIENRPHPERVIRVRALDKDAVLNARDERLGYH-KIIYS-LQGEHAMLFDINNTTGEIIVASG 1122
            |::.|.......|::|.|.|.|      ||..|.. |::|| |||:  ..|.|...||.|..|..
Zfish   156 ASVSEMSNVGAFVMKVTASDAD------DEAYGNSAKLVYSILQGQ--PYFSIEPETGVIRTALP 212

  Fly  1123 QTIDRERTPRIQLQIKAEDSPGRPTDAKQSVVELQIEVLDVNDNAPEFTQKKYSTVIPENAQIDS 1187
            ..| ||.....|:.|:|:|..|: .........:.|.:||||::.|.|....|....||:.:|.|
Zfish   213 NMI-RENREHYQVVIQAKDMAGQ-MGGLSGTTTVNITLLDVNNSPPRFPHSNYHLSTPESTEIGS 275

  Fly  1188 FVLQLEAVDADEGLGGEVRYELVNEGEANGLFKIDTKS----GLISTRRNLTGKGRAHPYVLIVR 1248
            .|.:::|.|||.|...|:.|.:: ||:...:|.|.|.|    |:|..::.|..:.| ..|.|.|:
Zfish   276 SVGRIKAYDADVGENAEMWYSIL-EGDGQDVFNIITDSTSQEGVIMVKKQLDYESR-RLYSLRVQ 338

  Fly  1249 AQDN--GNQMPKQPTLSTDTDVRIYIGDVSANDGVPYFLSPRVGQMANVTENAVTGAPVFQVIAS 1311
            ..:.  ..:..:|...|....|||.:.||   |..|.|  .|...:..|.|::..|:.:..|.|.
Zfish   339 VTNTHIDRRFEQQGPFSDTAIVRITVTDV---DEPPVF--SRALYIFEVDEDSPVGSSIGIVSAR 398

  Fly  1312 DPDDESTPSGTITYRILPDTPDAEAFVIDAHSGLITTRQSMDRETKDMYRILLEVSDNGQPKQSA 1376
            |||   |.|..:.|.|...|.....|.||:::|.|:|.|::||||...:.|.:..::.....|:.
Zfish   399 DPD---TISHLVKYTIDRHTDLERLFNIDSNNGTISTLQALDRETSKWHNISVLATELSTALQTR 460

  Fly  1377 TRILQIAILDVDDHEPRFAREADAGPLSMSVREEEPAGTIVGNFSALDED---LGENAAIDYVII 1438
            ..:. |.:.||:|:.|.||.:     ....|.|...||..:...||:|.|   :|........:|
Zfish   461 VPVF-IKVRDVNDNAPEFAMD-----FQTIVCENARAGQAIQTISAVDTDEPLVGHKFVFSLSVI 519

  Fly  1439 DGNNEQLFTIERNNESLA-ILKTKKPIDREQVESFTLTIKCLKLGEPGYKFIGD-PYDRQ-DLSH 1500
            :.|    |||..|.::.| ||..:...:|.:|.|:.|.:           .|.| .|..| ..|.
Zfish   520 NPN----FTIFDNEDNTAQILTRRSGFNRREVSSYLLPV-----------IISDNDYPIQSSTST 569

  Fly  1501 LRINVRVLDIDDNLPKFEQPDPTVGIRINVPIDT---------------VVTTLKASDADAEAPP 1550
            |.:.|...|...|:    |...|..:.::..:.|               :|....|.....:..|
Zfish   570 LTVRVCACDSHGNV----QTCSTEALLLSAGLSTGALVAILLCILILLMIVVLFAALRRQKKKEP 630

  Fly  1551 VGLSIENVTFVPQFY-------KRSRSLAVGNLHN-----------------LFTLNNRTGELRT 1591
            :.:|.|:|......|       :.:::..:|.|.|                 ||.. .||..|:.
Zfish   631 LIISKEDVRDNVVSYNDEGGGEEDTQAFDIGTLRNPEVIDTNKLRRDIMPEMLFPY-RRTSPLKD 694

  Fly  1592 GGSFADYVDGYFLMRVMANNSVQPKRQAHSNLKVF 1626
            .....|:::|.     :..|.:.|....:.:|..:
Zfish   695 NTDVRDFINGR-----LQENDLDPTAPPYDSLATY 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad74A	NP_648973.1	Cadherin_repeat	33..124	CDD:206637
		Cadherin_repeat	132..240	CDD:206637
		Cadherin_repeat	249..361	CDD:206637
		Cadherin_repeat	487..581	CDD:206637
		Cadherin_repeat	589..686	CDD:206637
		Cadherin_repeat	713..810	CDD:206637
		Cadherin_repeat	819..936	CDD:206637	189/749 (25%)
		Cadherin_repeat	953..1049	CDD:206637	19/101 (19%)
		Cadherin_repeat	1057..1166	CDD:206637	36/110 (33%)
		Cadherin_repeat	1175..1279	CDD:206637	33/109 (30%)
		Cadherin_repeat	1293..1390	CDD:206637	29/96 (30%)
		Cadherin_repeat	1402..1513	CDD:206637	30/116 (26%)
		Cadherin_repeat	1523..1628	CDD:206637	22/142 (15%)
cdh10b	XP_073774932.1	None