Protein Alignment tap and ATOH8

DIOPT Version :10

• Sequence 1: NP_524124.1
• Gene: tap / 39935
• FlyBaseID: FBgn0015550
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: XP_011531441.1
• Gene: ATOH8 / 84913
• HGNCID: 24126
• Length: 328
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 66/244 - (27%)
• Similarity: 98/244 - (40%)
• Gaps: 57/244 - (23%)

  Fly    27 DSGYEKSFETEAQLSSRRRLDFG---------TPPTPAIPQPYS---GGTWDAVPLSSPPAGFVG 79
            |:..|:......::|..|:..|.         |||.|..|.|.|   ||. :|.|...|     |
Human    91 DTAGERGGSRAPEVSDARKRCFALGAVGPGLPTPPPPPPPAPQSQAPGGP-EAQPFREP-----G 149

  Fly    80 LLDTSSNHSTRSGRTLVEHLNSRATNGVFDPPLTSTPVKSPEDPNAP-RPKR------KYAVGKN 137
            |          ..|.|:....:|.....  ||....|.:|...|..| ||..      .:.:..|
Human   150 L----------RPRILLCAPPARPAPSA--PPAPPAPPESTVRPAPPTRPGESSYSSISHVIYNN 202

  Fly   138 RVTRSRSP-----------TQVVKIKRFRRMKANDRERNRMHNLNDALEKLRVTLPSLPEETKLT 191
            ....|.||           :::..:::.||:.||.|||.|:|.::.|.|.||..:|......||:
Human   203 HQDSSASPRKRPGEATAASSEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLS 267

  Fly   192 KIEILRFAHNYIFALEQVLE---SGGSINLDLEKLQNFTLSGERITKEL 237
            |:.|||.|.|||.:|.::.:   |....||      :|:...:|.|:.|
Human   268 KLAILRIACNYILSLARLADLDYSADHSNL------SFSECVQRCTRTL 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tap	NP_524124.1	bHLH_TS_NGN	155..211	CDD:381434	25/55 (45%)
ATOH8	XP_011531441.1	bHLH_TS_ATOH8	224..291	CDD:381427	25/66 (38%)