Protein Alignment tap and Neurod2

DIOPT Version :10

• Sequence 1: NP_524124.1
• Gene: tap / 39935
• FlyBaseID: FBgn0015550
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: NP_062199.2
• Gene: Neurod2 / 54276
• RGDID: 3166
• Length: 382
• Species: Rattus norvegicus
• Alignment Length: 423
• Identity: 103/423 - (24%)
• Similarity: 140/423 - (33%)
• Gaps: 159/423 - (37%)

  Fly    18 DEDDDDASFDSGYEKSFETEAQLSSRRRLDFGTPPTPAIPQPYSGGTWDAVPLSSPPAGFVGLLD 82
            |.|||:...|.|                   ..||.|. |.|.||....|
  Rat    23 DGDDDEPRSDKG-------------------DAPPQPP-PAPGSGAPGPA--------------- 52

  Fly    83 TSSNHSTRSGRTLVEHLNSRAT-----NGVFDPPLTSTPVKSP-----------------EDPNA 125
                               |||     .|...|..|...||..                 ::...
  Rat    53 -------------------RATKPVSLRGEEVPEPTLAEVKEEGELGGEEEEEEEEEEGLDEAEG 98

  Fly   126 PRPKRKYAVGKNRVTRSRSPTQVVKIKRFRRMKANDRERNRMHNLNDALEKLRVTLPSLPEETKL 190
            .|||:: ...|.::|::|     ::..:.||.|||.|||||||:||.||:.||..:|...:..||
  Rat    99 ERPKKR-GPKKRKMTKAR-----LERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKL 157

  Fly   191 TKIEILRFAHNYIFALEQVLESG-------------------------GSINLDLEKLQNFTLSG 230
            :|||.||.|.|||:||.::|.||                         |.:.|:   .:||
  Rat   158 SKIETLRLAKNYIWALSEILRSGKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLN---SRNF---- 215

  Fly   231 ERITKELFDA----------LFVNPQPYP---LFGRMFPYGQGMAPLAQHQTAP----ASHAEQP 278
              :|::..|.          ..::|.|||   |.|.......|:...|.|....    |::....
  Rat   216 --LTEQGADGAGRFHGSGGPFAMHPYPYPCSRLAGAQCQAAGGLGGGAAHALRTHGYCAAYETLY 278

  Fly   279 PAMGGFQHGMDY-------PQQPPGFDFTGSMRFYHQQQQQP------HQPHHLQPNPQQESSPQ 330
            .|.||.....||       |..|| ....|:  |..:|...|      |...|....|....:
  Rat   279 AAAGGGGASPDYNSSEYEGPLSPP-LCLNGN--FSLKQDSSPDHEKSYHYSMHYSALPGSRPA-- 338

  Fly   331 QFSQEKYDLFRGSFDAAANLHSTNL---DSGIH 360
                 .:.|..||......:||.||   |..:|
  Rat   339 -----GHGLVFGSSAVRGGVHSENLLSYDMHLH 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tap	NP_524124.1	bHLH_TS_NGN	155..211	CDD:381434	32/55 (58%)
Neurod2	NP_062199.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..129		33/165 (20%)
		bHLH_TS_NeuroD2	88..180	CDD:381563	39/97 (40%)
		Nuclear localization signal. /evidence=ECO:0000255	107..113		1/5 (20%)
		Neuro_bHLH	180..310	CDD:463621	26/141 (18%)