Protein Alignment tap and NEUROG1

DIOPT Version :9

• Sequence 1: NP_524124.1
• Gene: tap / 39935
• FlyBaseID: FBgn0015550
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: NP_006152.2
• Gene: NEUROG1 / 4762
• HGNCID: 7764
• Length: 237
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 92/300 - (30%)
• Similarity: 118/300 - (39%)
• Gaps: 102/300 - (34%)

  Fly     7 AYSAGSQSFEFDEDDDDASFDSGYEKSFETEAQLSSRRRLDFGTPPTPAIPQPYSGGTWDAVPLS 71
            |.|:||....|..|::|.:                   ||.                  .|...|
Human    15 ASSSGSDLSGFLTDEEDCA-------------------RLQ------------------QAASAS 42

  Fly    72 SPPAGFVGLLDTSSNHSTRSGRTLVEHLNSRATNGVFDPPLTSTPVKSPEDPNAPRPKRKYAVGK 136
            .|||            ..|.|...:    |||:.           |...:|....|.:|:   |:
Human    43 GPPA------------PARRGAPNI----SRASE-----------VPGAQDDEQERRRRR---GR 77

  Fly   137 NRVTRSRSPTQVVKIKRFRRMKANDRERNRMHNLNDALEKLRVTLPSLPEETKLTKIEILRFAHN 201
            .||   ||...:..::|.||:||||||||||||||.||:.||..|||.|::|||||||.||||:|
Human    78 TRV---RSEALLHSLRRSRRVKANDRERNRMHNLNAALDALRSVLPSFPDDTKLTKIETLRFAYN 139

  Fly   202 YIFALEQVLESGGSINLDLEKLQNFTLSGERITKELFDALFVNPQPYP-LFGRMFP------YGQ 259
            ||:||.:.|           :|.:..|.|....:.|     :.||..| |.|...|      :|.
Human   140 YIWALAETL-----------RLADQGLPGGGARERL-----LPPQCVPCLPGPPSPASDAESWGS 188

  Fly   260 GMAPLAQHQTAPASHAEQPPAMGGFQHGMDYPQQPPGFDF 299
            |.|     ..:|.|....|.|...|    .|....|.|.|
Human   189 GAA-----AASPLSDPSSPAASEDF----TYRPGDPVFSF 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tap	NP_524124.1	HLH	155..207	CDD:278439	39/51 (76%)
NEUROG1	NP_006152.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	35..83		19/98 (19%)
		HLH	90..149	CDD:238036	42/69 (61%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	175..209		10/42 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145406
Domainoid	1	1.000	81	1.000	Domainoid score	I8498
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002069
OrthoInspector	1	1.000	-	-		otm42278
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19290
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4181
SonicParanoid	1	1.000	-	-		X1366
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.830