Protein Alignment tap and NEUROD2

DIOPT Version :9

• Sequence 1: NP_524124.1
• Gene: tap / 39935
• FlyBaseID: FBgn0015550
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: NP_006151.3
• Gene: NEUROD2 / 4761
• HGNCID: 7763
• Length: 382
• Species: Homo sapiens
• Alignment Length: 404
• Identity: 103/404 - (25%)
• Similarity: 143/404 - (35%)
• Gaps: 121/404 - (29%)

  Fly    18 DEDDDDASFDSGYEKSFETEAQLSSRRRLDFGTPPTPAIPQPYSGGTWDA---VPLSSPPAGFVG 79
            |.:||:...|.|                 |...||.|| |.|.:.|...|   |||.. ..|...
Human    23 DGEDDEPRSDKG-----------------DAPPPPPPA-PGPGAPGPARAAKPVPLRG-EEGTEA 68

  Fly    80 LLDTSSNHSTRSGRTLVEHLNSRATNGVFDPPLTSTPVKSPEDPNAPRPKRKYAVGKNRVTRSRS 144
            .|..........|.   |........|:             ::....|||:: ...|.::|::|
Human    69 TLAEVKEEGELGGE---EEEEEEEEEGL-------------DEAEGERPKKR-GPKKRKMTKAR- 115

  Fly   145 PTQVVKIKRFRRMKANDRERNRMHNLNDALEKLRVTLPSLPEETKLTKIEILRFAHNYIFALEQV 209
                ::..:.||.|||.|||||||:||.||:.||..:|...:..||:|||.||.|.|||:||.::
Human   116 ----LERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEI 176

  Fly   210 LESG-------------------------GSINLDLEKLQNFTLSGERITKELFDA--------- 240
            |.||                         |.:.|:   .:||      :|::..|.
Human   177 LRSGKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLN---SRNF------LTEQGADGAGRFHGSGG 232

  Fly   241 -LFVNPQPYP---LFGRMFPYGQGMAPLAQHQTAP----ASHAEQPPAMGGFQHGMDY------- 290
             ..::|.|||   |.|.......|:...|.|....    |::.....|.||.....||
Human   233 PFAMHPYPYPCSRLAGAQCQAAGGLGGGAAHALRTHGYCAAYETLYAAAGGGGASPDYNSSEYEG 297

  Fly   291 PQQPPGFDFTGSMRFYHQQQQQP------HQPHHLQPNPQQESSPQQFSQEKYDLFRGSFDAAAN 349
            |..|| ....|:  |..:|...|      |...|....|....:       .:.|..||......
Human   298 PLSPP-LCLNGN--FSLKQDSSPDHEKSYHYSMHYSALPGSRPT-------GHGLVFGSSAVRGG 352

  Fly   350 LHSTNL---DSGIH 360
            :||.||   |..:|
Human   353 VHSENLLSYDMHLH 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tap	NP_524124.1	HLH	155..207	CDD:278439	31/51 (61%)
NEUROD2	NP_006151.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..129		33/146 (23%)
		bHLH_TS_NeuroD2	88..180	CDD:381563	40/110 (36%)
		Nuclear localization signal. /evidence=ECO:0000255	107..113		1/5 (20%)
		Neuro_bHLH	180..310	CDD:403655	26/141 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145434
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4181
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.770