Protein Alignment tap and NEUROD1

DIOPT Version :10

• Sequence 1: NP_524124.1
• Gene: tap / 39935
• FlyBaseID: FBgn0015550
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: NP_002491.3
• Gene: NEUROD1 / 4760
• HGNCID: 7762
• Length: 356
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 93/305 - (30%)
• Similarity: 125/305 - (40%)
• Gaps: 64/305 - (20%)

  Fly    57 PQPYSGGTWDAVPLSSPPAGFVGLLDTSSNHSTRSGRTLVEHLNSR---ATNG----VFDPPLTS 114
            |||....:|....|||          ....|........:|.:|:.   ..||    ..|..|..
Human    14 PQPQGPPSWTDECLSS----------QDEEHEADKKEDDLETMNAEEDSLRNGGEEEDEDEDLEE 68

  Fly   115 TPVKSPEDPNAPRPKRKYAVGKNRVTRSRSPTQVVKIKRF--RRMKANDRERNRMHNLNDALEKL 177
            ...:..||.: .:|||: ...|.::|::|       ::||  ||||||.|||||||.||.||:.|
Human    69 EEEEEEEDDD-QKPKRR-GPKKKKMTKAR-------LERFKLRRMKANARERNRMHGLNAALDNL 124

  Fly   178 RVTLPSLPEETKLTKIEILRFAHNYIFALEQVLESGGSINLDLEKLQNFTLSG--ERITKELFDA 240
            |..:|...:..||:|||.||.|.|||:||.::|.||.|  .||.........|  :..|..:...
Human   125 RKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKS--PDLVSFVQTLCKGLSQPTTNLVAGC 187

  Fly   241 LFVNPQPYPLFGRMFPYGQGMAPLAQH-QTAPASHAEQPPAMGGFQHGMDYPQQPPGFDFT--GS 302
            |.:||:.:     :....|.|.|   | .||.||....|           |..|.||....  |:
Human   188 LQLNPRTF-----LPEQNQDMPP---HLPTASASFPVHP-----------YSYQSPGLPSPPYGT 233

  Fly   303 MRFYHQQQQQPHQPHHLQPNPQQESSPQQ--FSQEKYDLFRGSFD 345
            |...|        ..|::|.|...|:..:  |.....|....|||
Human   234 MDSSH--------VFHVKPPPHAYSAALEPFFESPLTDCTSPSFD 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tap	NP_524124.1	bHLH_TS_NGN	155..211	CDD:381434	33/55 (60%)
NEUROD1	NP_002491.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..94		21/91 (23%)
		bHLH_TS_NeuroD1	75..160	CDD:381562	44/93 (47%)
		Nuclear localization signal. /evidence=ECO:0000255	87..93		1/5 (20%)
		Neuro_bHLH	160..284	CDD:463621	34/140 (24%)