DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tap and hlh-8

DIOPT Version :9

Sequence 1:	NP_524124.1	Gene:	tap / 39935	FlyBaseID:	FBgn0015550	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_509367.1	Gene:	hlh-8 / 181069	WormBaseID:	WBGene00001953	Length:	178	Species:	Caenorhabditis elegans

Alignment Length:	212	Identity:	56/212 - (26%)
Similarity:	79/212 - (37%)	Gaps:	63/212 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 RPKRKYAVGKNRVTRSRSPTQVVKIKRFRRMKANDRERNRMHNLNDALEKLRVTLPSLPEETKLT 191
            |.|.:..|.||.|...:           :|..||.|||.|...||||...||..:||:|.: |::
Worm     4 RRKGERVVRKNEVENVQ-----------QRACANRRERQRTKELNDAFTLLRKLIPSMPSD-KMS 56

  Fly   192 KIEILRFAHNYIFALEQVLESGGSINLDLEKLQNFTLSGERITKELFDALFVNPQPYPLFGRMFP 256
            ||..||.|.:||..|:::.::|.       ||...::..|:....|..|.           .|:.
Worm    57 KIHTLRIATDYISFLDEMQKNGC-------KLYGHSIFDEKRGYNLQSAF-----------NMWR 103

  Fly   257 YGQGMAPLA-QHQTAPASHAEQPPAMGGFQHGMDYPQQPPGFDFTGSMRFYHQQQQQPHQPHHLQ 320
            ...|..|:| ..|..|...|..||..         |...|                    ||.|.
Worm   104 GNNGYTPIAGPSQLPPLQSAHIPPPA---------PSSIP--------------------PHCLM 139

  Fly   321 PNPQQESSP---QQFSQ 334
            |.|..::.|   |:|.:
Worm   140 PQPWYQTCPPPKQEFHE 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tap	NP_524124.1	HLH	155..207	CDD:278439	24/51 (47%)
hlh-8	NP_509367.1	HLH	21..71	CDD:278439	24/50 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910