Protein Alignment tap and Neurod2

DIOPT Version :9

• Sequence 1: NP_524124.1
• Gene: tap / 39935
• FlyBaseID: FBgn0015550
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: NP_035025.3
• Gene: Neurod2 / 18013
• MGIID: 107755
• Length: 383
• Species: Mus musculus
• Alignment Length: 418
• Identity: 103/418 - (24%)
• Similarity: 143/418 - (34%)
• Gaps: 148/418 - (35%)

  Fly    18 DEDDDDASFDSGYEKSFETEAQLSSRRRLDFGTPPTPAIPQPYSGGTWDAVPLSSPPAGFVGLLD 82
            |.|||:...|.|                   ..||.|. |.|.||....|  .::.|.
Mouse    23 DGDDDEPRSDKG-------------------DAPPQPP-PAPGSGAPGPA--RAAKPV------- 58

  Fly    83 TSSNHSTRSGRTLVEHLNSRATNGVFDPPLTSTPVKSP-----------------EDPNAPRPKR 130
                 |.|.|..:              |..|...||..                 ::....|||:
Mouse    59 -----SLRGGEEI--------------PEPTLAEVKEEGELGGEEEEEEEEEEGLDEAEGERPKK 104

  Fly   131 KYAVGKNRVTRSRSPTQVVKIKRFRRMKANDRERNRMHNLNDALEKLRVTLPSLPEETKLTKIEI 195
            : ...|.::|::|     ::..:.||.|||.|||||||:||.||:.||..:|...:..||:|||.
Mouse   105 R-GPKKRKMTKAR-----LERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIET 163

  Fly   196 LRFAHNYIFALEQVLESG-------------------------GSINLDLEKLQNFTLSGERITK 235
            ||.|.|||:||.::|.||                         |.:.|:   .:||      :|:
Mouse   164 LRLAKNYIWALSEILRSGKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLN---SRNF------LTE 219

  Fly   236 ELFDA----------LFVNPQPYP---LFGRMFPYGQGMAPLAQHQTAP----ASHAEQPPAMGG 283
            :..|.          ..::|.|||   |.|.......|:...|.|....    |::.....|.||
Mouse   220 QGADGAGRFHGSGGPFAMHPYPYPCSRLAGAQCQAAGGLGGGAAHALRTHGYCAAYETLYAAAGG 284

  Fly   284 FQHGMDY-------PQQPPGFDFTGSMRFYHQQQQQP------HQPHHLQPNPQQESSPQQFSQE 335
            .....||       |..|| ....|:  |..:|...|      |...|....|....:
Mouse   285 GGASPDYNSSEYEGPLSPP-LCLNGN--FSLKQDSSPDHEKSYHYSMHYSALPGSRPT------- 339

  Fly   336 KYDLFRGSFDAAANLHSTNL---DSGIH 360
            .:.|..||......:||.||   |..:|
Mouse   340 GHGLVFGSSAVRGGVHSENLLSYDMHLH 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tap	NP_524124.1	HLH	155..207	CDD:278439	31/51 (61%)
Neurod2	NP_035025.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..130		33/160 (21%)
		bHLH_TS_NeuroD2	89..181	CDD:381563	39/97 (40%)
		Nuclear localization signal. /evidence=ECO:0000255	108..114		1/5 (20%)
		Neuro_bHLH	181..311	CDD:372170	26/141 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835500
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4181
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.770