DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tap and OLIG3

DIOPT Version :9

Sequence 1:	NP_524124.1	Gene:	tap / 39935	FlyBaseID:	FBgn0015550	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_786923.1	Gene:	OLIG3 / 167826	HGNCID:	18003	Length:	272	Species:	Homo sapiens

Alignment Length:	219	Identity:	60/219 - (27%)
Similarity:	84/219 - (38%)	Gaps:	64/219 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 RMKANDRERNRMHNLNDALEKLRVTLPSL--PEETKLTKIEILRFAHNYIFALEQVLESGGSINL 218
            |:|.|.|||.|||:||.|::.||..:|..  |...||:||..|..|.|||..|...||
Human    85 RLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTSSLE------- 142

  Fly   219 DLEKLQNFTLSGERIT-----------KELFDALFVNPQPYPLFGRMFPYGQGMAPLAQHQTAPA 272
            ::::|......|....           .....|..|:| .:|:.|.....|...:||:. .:.||
Human   143 EMKRLVGEIYGGHHSAFHCGTVGHSAGHPAHAANSVHP-VHPILGGALSSGNASSPLSA-ASLPA 205

  Fly   273 ------SHA-----EQPPAM---GGFQH--GMDYP----QQPPGFDFTGSMRFYHQQQQQPHQPH 317
                  .|:     ..|||:   .||||  |:..|    |.||                    |.
Human   206 IGTIRPPHSLLKAPSTPPALQLGSGFQHWAGLPCPCTICQMPP--------------------PP 250

  Fly   318 HLQPNPQQESSPQQFSQEKYDLFR 341
            ||  :....::..:.|.|..||.:
Human   251 HL--SALSTANMARLSAESKDLLK 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tap	NP_524124.1	HLH	155..207	CDD:278439	25/52 (48%)
OLIG3	NP_786923.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..71
OLIG3	NP_786923.1	HLH	85..138	CDD:306515	25/52 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145429
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19290
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840