Protein Alignment brv2 and pkd1b

DIOPT Version :9

• Sequence 1: NP_648970.2
• Gene: brv2 / 39932
• FlyBaseID: FBgn0036712
• Length: 736
• Species: Drosophila melanogaster
• Sequence 2: XP_021335980.1
• Gene: pkd1b / 565697
• ZFINID: ZDB-GENE-100707-2
• Length: 4007
• Species: Danio rerio
• Alignment Length: 638
• Identity: 121/638 - (18%)
• Similarity: 207/638 - (32%)
• Gaps: 242/638 - (37%)

  Fly    24 CFVLVSIFSGFMHEPQRFKTMLVTIVLV-----FFFQYLILEPIRFFIQSIDYAT---------- 73
            |..:|.::.      ..|.:.:|.:.||     .....|:|||:...||::..||
Zfish  3176 CLAVVGLYG------SSFTSSVVLMWLVSTLSAVLTSALLLEPLAICIQALYLATVVRPVDPEVE 3234

  Fly    74 --WPQEDPPYRAEEGGPTMDH----IGYLKI-----RLRSLRSELLISEGHTNEMLNQKYKHIAG 127
              ..||....|:||......|    .|.|:.     :||:||:                   :..
Zfish  3235 ERLAQETEVRRSEEDFRDKVHPLCGYGLLQAKEEARKLRTLRA-------------------LMR 3280

  Fly   128 DLLLYGSYFIALMLMVVLQEDHTNYYNTNNMQRLFWDNTSVTFGLSQVYFIYQVHSYMKITLVEA 192
            ..|:|     .|.|:|||..::..:....:.:||                    ||.:|.||:.|
Zfish  3281 SCLVY-----MLFLLVVLMVNYQEHVQMADSRRL--------------------HSAIKHTLISA 3320

  Fly   193 FYAQKTN--GYEGWWAMEQW--QKI-------------GVVRLRQMRPVD-CHIGLGKPEWDKKT 239
             .|.|..  ...||...|||  :|:             |..||:::...| |..|
Zfish  3321 -SAGKPGLMKLSGWMNAEQWINEKLTSHLYENPSLLLTGPARLQKVYFQDFCSQG---------- 3374

  Fly   240 YAPEWRLPYHRMHYTEKFWRIYDPF-------VPAEFEPSFLN-GLLLNYDHYGYLLNYPEVAGY 296
                                |.|.|       :|.....|..| |...:..|   ..|.|.::.:
Zfish  3375 --------------------IRDQFQSGRLSLMPTAHVSSHANPGQQTSTAH---SKNTPALSTW 3416

  Fly   297 -----------VVLMMSTKINCLKQI-EYLRDYSWLDKNTSALFIDLTMYNADANLFTLITLRVE 349
                       ..|::.......:|| ..|:...|:...|.|:.|:.|.|:...::...:::.::
Zfish  3417 QKRALCAFSQTEELVLGNNTEYTRQILSDLQKEKWMTTGTKAVLIEFTQYHKQTSILAPVSILLD 3481

  Fly   350 NSPFG-----IQLPRVHVDSVSMLGNVETRSNSELLILFVYTVLVILFA--------RGVFTKIW 401
            .:..|     |.:...|:..:         |..:|.:  ..||:::|||        |.:..|
Zfish  3482 QTQTGRILAFISIQPFHISPL---------SGPDLHV--TLTVVLLLFALCFLSTEVRALIRK-- 3533

  Fly   402 HHPAA-AHEAWTMVDLAIYILNVFLTVLAIMRDIETDALLQIIETAT---------KGQYLDFQR 456
              |:. ..:||..          |.|:||::........|..:.|.|         ...:.||..
Zfish  3534 --PSQYLRQAWCW----------FQTLLALLALAAAVLRLYFLYTTTVCISRYRSIPSSFADFHS 3586

  Fly   457 PLRLHQMLFIVKGFLVCITTLRLWKVLQFAS--------VFQHFTQTLFSAWRAVASLGVIILVV 513
            ...:.:....:...|:.:..|::..:|||..        ::|.|.|.          .||:.|::
Zfish  3587 AATVARKSNQLSAILLTLLALKMVGILQFVRRWLVMGRVIWQVFPQI----------CGVVFLLL 3641

  Fly   514 LMAIGITLAVPNGNNAVVFSHMVQSVVTCMWYSMGFNGDIHPADFFHGGRILG 566
            |:.:             :|||:..         |.|:|.:      .|.|.||
Zfish  3642 LLLL-------------LFSHIGM---------MLFSGSV------EGFRTLG 3666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brv2	NP_648970.2	PKD_channel	169..596	CDD:285288	86/467 (18%)
pkd1b	XP_021335980.1	PCC	25..2314	CDD:188093
		GPS	2590..2636	CDD:321989
		PLAT_polycystin	2697..2815	CDD:238850
		PKD_channel	3302..3720	CDD:332708	88/482 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3599
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1276906at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820