DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment brv2 and F27C1.11

DIOPT Version :9

Sequence 1:	NP_648970.2	Gene:	brv2 / 39932	FlyBaseID:	FBgn0036712	Length:	736	Species:	Drosophila melanogaster
Sequence 2:	NP_001362170.1	Gene:	F27C1.11 / 3565116	WormBaseID:	WBGene00017858	Length:	1271	Species:	Caenorhabditis elegans

Alignment Length:	362	Identity:	69/362 - (19%)
Similarity:	126/362 - (34%)	Gaps:	112/362 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 QEDPPYRAEEGGPTMDHIGYLKIRLRSLRSELLISEGHTNEMLNQKYKHIAGDLLLYGSYFIALM 140
            :|:.||| :.|....:.:|....::::......:.:.|...:..::.|.  .::|.|...||...
Worm   504 EEEDPYR-DIGTAERERLGEAATKIQAAYKGYTVRKKHVQFLKEKERKE--QEILDYEKQFIHYT 565

  Fly   141 LMVVLQEDHTNYYNTNNMQRLFWDNTSVTFGL---SQVYFIYQVHSYMKITLVEAFYAQKTNGYE 202
            ..|:|..                     .|||   :.::|:....:...    |..|.|.    :
Worm   566 FEVMLGN---------------------RFGLDFDTPLFFVLHGENGSS----EKIYTQA----D 601

  Fly   203 GW-------WAMEQW-------QKIGVVRLRQMRPVDCHIGLGKPEWDKKTY------------A 241
            .|       :..|.|       .|:||     :..:|  :|..:..:...|:            |
Worm   602 DWLFLPSSCYDPESWILSSTRSLKLGV-----LTSID--VGHEQEGYGAGTFIDKIVITEDEKGA 659

  Fly   242 PEWRLPYHRMHYTEKFWRIYDPFVPAEFEPSFLNGLL---LNYDHYGYLLNYPEVA-GYVVLMMS 302
            .|.|    |.::..:.|          |:...::||:   :..:.:.||::..|.. |.|.....
Worm   660 KECR----RFYFQVEKW----------FDSGQVDGLIVRNIKVNSFLYLVSSTERGEGVVERKKE 710

  Fly   303 TK---------INC--------LKQIEYLRDYSWL--DKNTSALFID---LTMYNAD-ANLFTLI 344
            ||         :|.        ||.|.| .|.:||  |....:|..|   :.....| .|:..|.
Worm   711 TKGRWEFRLHTLNSDLGGTTSHLKIIGY-GDENWLADDIPNDSLLRDPSQVPRIQVDFGNIGRLQ 774

  Fly   345 TLRVENSPFGIQLPRVHVDSVSMLGNVETRSNSELLI 381
            .:|.|..|.|.| |..:::.|. ..:::||....|::
Worm   775 KVRFEIQPAGDQ-PNYYLEYVE-AQDLDTRERCVLMV 809

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brv2	NP_648970.2	PKD_channel	169..596	CDD:285288	55/269 (20%)
F27C1.11	NP_001362170.1	DCX	26..94	CDD:340456
		DUF2967	<89..>407	CDD:371408
		PLAT	564..684	CDD:381752	26/169 (15%)
		PLAT	713..823	CDD:238061	24/100 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3599
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900