Protein Alignment brv2 and Pkd2

DIOPT Version :9

• Sequence 1: NP_648970.2
• Gene: brv2 / 39932
• FlyBaseID: FBgn0036712
• Length: 736
• Species: Drosophila melanogaster
• Sequence 2: NP_609561.2
• Gene: Pkd2 / 34651
• FlyBaseID: FBgn0041195
• Length: 924
• Species: Drosophila melanogaster
• Alignment Length: 777
• Identity: 155/777 - (19%)
• Similarity: 284/777 - (36%)
• Gaps: 199/777 - (25%)

  Fly    67 QSIDYATWPQEDPPYRAEEGGPTMDHIGYLKIRLRSLRSELLISEGHTNEMLNQKYKHIAGDLLL 131
            :|:..:|.|.....:||    |::            :.:..|.:...||.:|....:.:...|:.
  Fly   192 KSVGSSTPPSPSRGHRA----PSI------------IAASALQNRAKTNRILYTTDEEVREALVE 240

  Fly   132 YGSYFIALML--MVVLQEDHT-NYYNTNNMQRLFWDN-----TSVTFGLSQVYFIYQVHSYMK-- 186
            :..:.|.|:|  :|||...|| .:|..:.|::||.:.     .|||.|..::..:.....|:|
  Fly   241 FSVFIIFLILTSLVVLSVRHTYMFYFNDTMKKLFTNREMVVAPSVTVGFEKLITVPDWWDYLKYN 305

  Fly   187 --------ITLVEAFYAQKTN-GYEGWWAMEQWQKIGVVRLRQMRPVDCHIGLGKPEWDKKTYAP 242
                    :|.::...|..|: ..||   .||..:.|..:..:..|.:. :|....|      ||
  Fly   306 FLVTLHGDLTFMDDAQANLTSMPPEG---SEQGSEQGSEQGSEQSPEEV-VGEAPEE------AP 360

  Fly   243 EW-RL---------PY-----HR------------------------------------MHYTEK 256
            |. ||         ||     ||                                    .|:.|.
  Fly   361 EMDRLQEDFKYNGNPYIDLRGHRRAKRQSGVDGNSEDGSEDVSGNYLKDDSDSIQANMSFHHLEG 425

  Fly   257 FWRIYDPF---------VPAEFEPSFLNGLLLNYDHYGY-------------------------- 286
            ...:|:..         :....|..::|...:.|.:..|
  Fly   426 RVFLYENLLLGPPRLRQIRVRKESCYVNDAFIRYFNTCYAAYSSGAEDRKPMHKGSPFRTMHDLD 490

  Fly   287 ------LLNYPEVAGYVVLMMSTKINCLKQIEYLRDYSWLDKNTSALFIDLTMYNADANLFTLIT 345
                  :|.:....||.|.:...|...:|.|..|:|..|||:.:....::..::|.:.::|..|.
  Fly   491 STPIWTVLAFYRTGGYTVNLDYDKDRNVKIINDLKDIHWLDRGSRLCLVEFNLFNENTDIFQSIK 555

  Fly   346 LRVENSPFGIQLPRVHVDSVSMLGNVETRSNSELLILFVYTVLVILFARGVFTKIWHHPAAAH-- 408
            |..|..|.|..:|:.|:.:|.|......||....:|...:.::||.:.....|:|.......:
  Fly   556 LIAEIPPTGGVIPQAHLQTVKMYSFFTDRSMLMTVIYIFWYIMVIYYTIYEITEIRKSGIKIYFC 620

  Fly   409 EAWTMVDLAI----YILNVF-----LTVLAIMRDIETDALLQIIETATKGQYLDFQRPLRLHQML 464
            ....::|.||    |:..|:     ..|:::.....:|...|.::.      |.|...:.:..|.
  Fly   621 SMLNILDCAILLGCYLALVYNIWHSFKVMSLTARAHSDVTYQSLDV------LCFWNIIYVDMMA 679

  Fly   465 FIVKGFLVCITTLRLWKVLQFASVFQHFTQTLFSAWRAVASLGVIILVVLMA---IGITLAVPNG 526
            .:  .|||.|   :::|.:.|......||.||....:.:|...::..:|.:|   :|:.|.   |
  Fly   680 IL--AFLVWI---KIFKFISFNKTLVQFTTTLKRCSKDLAGFSLMFGIVFLAYAQLGLLLF---G 736

  Fly   527 NNAVVFSHMVQSVVTCMWYSMGFNGDIHPADFFH-----GGRILGILLYLALVFLLAIILMNVFA 586
            .....|.:.:.|::|.:...:|        ||.:     ..|:||.:.:|..:.|:..||:|:|.
  Fly   737 TKHPDFRNFITSILTMIRMILG--------DFQYNLIEQANRVLGPIYFLTYILLVFFILLNMFL 793

  Fly   587 SVIYDYFNET-SRILKEHSNRSSITFLEFLHVEYADLFGDAF---RCLRKTYESRGHTVAENVEL 647
            ::|.:.:|.. ..|.:..|:..|..        |..|.|..:   .|.||   .|.|..|...|
  Fly   794 AIIMETYNTVKGEITQGRSHLGSYI--------YRKLSGMLYWITHCGRK---RRHHPQASETE- 846

  Fly   648 ELNRRELIKFKRDLIKSPQELKRALLTEEQRSADYRLRGEK--LFKLMAILNLQVEILERMV 707
            :.:....:....|   ...|:::.:...||:......:||.  :.:|...:.|..||||:::
  Fly   847 DKDAEHDVGAAHD---ETHEIRKNMTPAEQQYFKDIPQGENQDMVRLNNRVGLLEEILEKLI 905

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brv2	NP_648970.2	PKD_channel	169..596	CDD:285288	105/548 (19%)
Pkd2	NP_609561.2	PKD_channel	402..803	CDD:285288	81/422 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456385
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3599
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10877
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840